|
|
eF-site ID
|
1mr1-A |
|
PDB Code
|
1mr1 |
|
Chain
|
A |
|
click to enlarge
|
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Title
|
Crystal Structure of a Smad4-Ski Complex |
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Classification
|
SIGNALING PROTEIN |
|
Compound
|
Mothers against decapentaplegic homolog 4 |
|
Source
|
null (SKI_HUMAN) |
|
|
Sequence
|
A: |
APEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSG
GDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVW
VRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVF
DLRQCHRQMQQQAATAQAAAAAQVDDLRRLCILRMSFVKG
WGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
428 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
2)
|
chain |
A |
| residue |
507 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
3)
|
chain |
A |
| residue |
519 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:19135894
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
4)
|
chain |
A |
| residue |
515 |
| type |
SITE |
| sequence |
R
|
| description |
Necessary for heterotrimerization
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|