eF-site ID 1mir-A PDB Code 1mir Chain A click to enlarge Title RAT PROCATHEPSIN B Classification HYDROLASE Compound PROCATHEPSIN B Source (CATB_RAT) Sequence A:  SDDMINYINKQNTTWQAGRNFYNVDISYLKKLCGTVLGGP KLPERVGFSEDINLPESFDAREQWSNCPTIAQIRDQGSCG SSWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQC GDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPP CEHHVNGARPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYG YTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFLTYKSGV YKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNADWGD NGFFKILRGENHCGIESEIVAGIPRTQQYWGRF Description Functional site 1) chain A residue 29 type sequence S description ACTIVE SITE WITH CYS 29 MUTATED TO SER. source : CYA 2) chain A residue 199 type sequence H description ACTIVE SITE WITH CYS 29 MUTATED TO SER. source : CYA 3) chain A residue 219 type sequence N description ACTIVE SITE WITH CYS 29 MUTATED TO SER. source : CYA 4) chain A residue 203 type MOD_RES sequence I description N6-acetyllysine => ECO:0000250|UniProtKB:P10605 source Swiss-Prot : SWS_FT_FI4 5) chain A residue 175 type CARBOHYD sequence T description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:6574504 source Swiss-Prot : SWS_FT_FI5 6) chain A residue 91 type ACT_SITE sequence G description ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10088, ECO:0000269|PubMed:7890671, ECO:0000269|PubMed:8740363 source Swiss-Prot : SWS_FT_FI1 7) chain A residue 191-201 type prosite sequence EAGDVMGGHAI description PEROXIDASE_1 Peroxidases proximal heme-ligand signature. EAGDVMGGHAI source prosite : PS00435 8) chain A residue 197-207 type prosite sequence GGHAIRILGWG description THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. GGHAIRILGWG source prosite : PS00639 9) chain A residue 214-233 type prosite sequence YWLVANSWNADWGDNGFFKI description THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YWLvANSWnadWGdnGFFkI source prosite : PS00640

Display surface Download Links