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eF-site ID
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1maz-A |
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PDB Code
|
1maz |
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Chain
|
A |
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click to enlarge
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Title
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X-RAY STRUCTURE OF BCL-XL, AN INHIBITOR OF PROGRAMMED CELL DEATH |
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Classification
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APOPTOSIS |
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Compound
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Bcl-2-like protein 1 |
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Source
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Homo sapiens (Human) (BCLX_HUMAN) |
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Sequence
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A: |
MSQSNRELVVDFLSYKLSQKGYSWSQFIPMAAVKQALREA
GDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRD
GVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATY
LNDHLEPWIQENGGWDTFVELYG
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Description
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Functional site
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1)
|
chain |
A |
| residue |
130-148 |
| type |
prosite |
| sequence |
LFRDGVNWGRIVAFFSFGG
|
| description |
BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. LFrDGv.NWGRIVAFFsFGG
|
| source |
prosite : PS01080
|
|
|
2)
|
chain |
A |
| residue |
181-192 |
| type |
prosite |
| sequence |
WIQENGGWDTFV
|
| description |
BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIqenGGWDtFV
|
| source |
prosite : PS01258
|
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3)
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chain |
A |
| residue |
86-100 |
| type |
prosite |
| sequence |
VKQALREAGDEFELR
|
| description |
BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. VkqaLReAGDEFELR
|
| source |
prosite : PS01259
|
|
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4)
|
chain |
A |
| residue |
4-24 |
| type |
prosite |
| sequence |
SNRELVVDFLSYKLSQKGYSW
|
| description |
BH4_1 Apoptosis regulator, Bcl-2 family BH4 motif signature. SNRELVvDFLSYKLSQKGYsW
|
| source |
prosite : PS01260
|
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