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|
eF-site ID
|
1m2s_8-A |
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PDB Code
|
1m2s |
|
Model
|
8 |
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Chain
|
A |
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click to enlarge
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Title
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Solution Structure of A New Potassium Channels Blocker from the Venom of Chinese Scorpion Buthus martensi Karsch |
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Classification
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TOXIN |
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Compound
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Toxin BmTX3 |
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Source
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ORGANISM_COMMON: Chinese scorpion; ORGANISM_SCIENTIFIC: Mesobuthus martensii; |
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Sequence
|
A: |
FGLIDVKCFASSECWTACKKVTGSGQGKCQNNQCRCY
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Description
|
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Functional site
|
|
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1)
|
chain |
A |
| residue |
28 |
| type |
SITE |
| sequence |
K
|
| description |
Basic residue of the functional dyad => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
2)
|
chain |
A |
| residue |
16 |
| type |
SITE |
| sequence |
T
|
| description |
Important for the inhibitory effect on KCNMA1 channels
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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3)
|
chain |
A |
| residue |
14-36 |
| type |
prosite |
| sequence |
CWTACKKVTGSGQGKCQNNQCRC
|
| description |
SCORP_SHORT_TOXIN Scorpion short toxins signature. CwtaCkkvtgsgq.GKCQnnqCrC
|
| source |
prosite : PS01138
|
|
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4)
|
chain |
A |
| residue |
37 |
| type |
SITE |
| sequence |
Y
|
| description |
Aromatic residue of the functional dyad => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI3
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