|
eF-site ID
|
1m2s_4-A |
PDB Code
|
1m2s |
Model
|
4 |
Chain
|
A |
|
click to enlarge
|
|
Title
|
Solution Structure of A New Potassium Channels Blocker from the Venom of Chinese Scorpion Buthus martensi Karsch |
Classification
|
TOXIN |
Compound
|
Toxin BmTX3 |
Source
|
ORGANISM_COMMON: Chinese scorpion; ORGANISM_SCIENTIFIC: Mesobuthus martensii; |
|
Sequence
|
A: |
FGLIDVKCFASSECWTACKKVTGSGQGKCQNNQCRCY
|
|
Description
|
|
Functional site
|
|
1)
|
chain |
A |
residue |
14-36 |
type |
prosite |
sequence |
CWTACKKVTGSGQGKCQNNQCRC
|
description |
SCORP_SHORT_TOXIN Scorpion short toxins signature. CwtaCkkvtgsgq.GKCQnnqCrC
|
source |
prosite : PS01138
|
|
2)
|
chain |
A |
residue |
16 |
type |
SITE |
sequence |
T
|
description |
Important for the inhibitory effect on KCNMA1 channels
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
3)
|
chain |
A |
residue |
28 |
type |
SITE |
sequence |
K
|
description |
Basic residue of the functional dyad => ECO:0000250
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
4)
|
chain |
A |
residue |
37 |
type |
SITE |
sequence |
Y
|
description |
Aromatic residue of the functional dyad => ECO:0000250
|
source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|