eF-site ID 1m0w-AB PDB Code 1m0w Chain A, B click to enlarge Title Yeast Glutathione Synthase Bound to gamma-glutamyl-cysteine, AMP-PNP and 2 Magnesium Ions Classification LIGASE Compound glutathione synthetase Source (GSHB_YEAST) Sequence A:  PSKDQLNELIQEVNQWAITNGLSMYPPKFEENPSNASVSP VTIYPTPIPRKCFDEAVQIQPVFNELYARITQDMAQPDSY LHKTTEALALSDSEFTGKLWSLYLATLKSAQYKKQNFRLG IFRSDYLIDKKKGTEQIKQVEFNTVSVSFAGLSEKVDRLH SYLNRANKYDPKGPIYNDQNMVISDSGYLLSKALAKAVES YKSQQSDPIVAFIVQRNERNVFDQKVLELNLLEKFGTKSV RLTFDDVNDKLFIDDKTGKLFIRDTEQEIAVVYYRTGYTT TDYTSEKDWEARLFLEKSFAIKAPDLLTQLSGSKKIQQLL TDEGVLGKYISDAEKKSSLLKTFVKIYPLDDTKLGREGKR LALSEPSKYVLKPQREGGGNNVYKENIPNFLKGIEERHWD AYILMELIEPELNENNIILRDNKSYNEPIISELGIYGCVL FNDEQVLSNEFSGSLLRSKFNTSNEGGVAAGFGCLDSIIL Y B:  PPSKDQLNELIQEVNQWAITNGLSMYPPKFEENPSNASVS PVTIYPTPIPRKCFDEAVQIQPVFNELYARITQDMAQPDS YLHKTTEALALSDSEFTGKLWSLYLATLKSAQYKKQNFRL GIFRSDYLIDKKKGTEQIKQVEFNTVSVSFAGLSEKVDRL HSYLNRANKYDPKGPIYNDQNMVISDSGYLLSKALAKAVE SYKSQQDPIVAFIVQRNERNVFDQKVLELNLLEKFGTKSV RLTFDDVNDKLFIDDKTGKLFIRDTEQEIAVVYYRTGYTT TDYTSEKDWEARLFLEKSFAIKAPDLLTQLSGSKKIQQLL TDEGVLGKYISDAEKKSSLLKTFVKIYPLDDTKLGREGKR LALSEPSKYVLKPQREGNNVYKENIPNFLKGIEERHWDAY ILMELIEPELNENNIILRDNKSYNEPIISELGIYGCVLFN DEQVLSNEFSGSLLRSKFNTSNEGGVAAGFGCLDSIILY Description Functional site 1) chain A residue 146 type sequence E description BINDING SITE FOR RESIDUE MG A 502 source : AC1 2) chain B residue 1146 type sequence E description BINDING SITE FOR RESIDUE MG B 1502 source : AC2 3) chain A residue 146 type sequence E description BINDING SITE FOR RESIDUE MG A 503 source : AC3 4) chain A residue 386 type sequence E description BINDING SITE FOR RESIDUE MG A 503 source : AC3 5) chain B residue 1146 type sequence E description BINDING SITE FOR RESIDUE MG B 1503 source : AC4 6) chain B residue 1386 type sequence E description BINDING SITE FOR RESIDUE MG B 1503 source : AC4 7) chain A residue 136 type sequence K description BINDING SITE FOR RESIDUE SO4 A 506 source : AC5 8) chain A residue 137 type sequence K description BINDING SITE FOR RESIDUE SO4 A 506 source : AC5 9) chain A residue 273 type sequence R description BINDING SITE FOR RESIDUE SO4 A 506 source : AC5 10) chain A residue 163 type sequence R description BINDING SITE FOR RESIDUE SO4 A 507 source : AC6 11) chain A residue 113 type sequence K description BINDING SITE FOR RESIDUE SO4 B 508 source : AC7 12) chain A residue 114 type sequence S description BINDING SITE FOR RESIDUE SO4 B 508 source : AC7 13) chain B residue 1366 type sequence R description BINDING SITE FOR RESIDUE SO4 B 508 source : AC7 14) chain B residue 1370 type sequence R description BINDING SITE FOR RESIDUE SO4 B 508 source : AC7 15) chain B residue 1136 type sequence K description BINDING SITE FOR RESIDUE SO4 B 509 source : AC8 16) chain B residue 1137 type sequence K description BINDING SITE FOR RESIDUE SO4 B 509 source : AC8 17) chain B residue 1273 type sequence R description BINDING SITE FOR RESIDUE SO4 B 509 source : AC8 18) chain B residue 1163 type sequence R description BINDING SITE FOR RESIDUE SO4 B 510 source : AC9 19) chain A residue 389 type sequence G description BINDING SITE FOR RESIDUE SO4 A 511 source : BC1 20) chain A residue 391 type sequence N description BINDING SITE FOR RESIDUE SO4 A 511 source : BC1 21) chain A residue 393 type sequence Y description BINDING SITE FOR RESIDUE SO4 A 511 source : BC1 22) chain B residue 1389 type sequence G description BINDING SITE FOR RESIDUE SO4 B 512 source : BC2 23) chain B residue 1390 type sequence N description BINDING SITE FOR RESIDUE SO4 B 512 source : BC2 24) chain B residue 1391 type sequence N description BINDING SITE FOR RESIDUE SO4 B 512 source : BC2 25) chain B residue 1393 type sequence Y description BINDING SITE FOR RESIDUE SO4 B 512 source : BC2 26) chain A residue 145 type sequence V description BINDING SITE FOR RESIDUE ANP A 504 source : BC3 27) chain A residue 146 type sequence E description BINDING SITE FOR RESIDUE ANP A 504 source : BC3 28) chain A residue 324 type sequence K description BINDING SITE FOR RESIDUE ANP A 504 source : BC3 29) chain A residue 382 type sequence K description BINDING SITE FOR RESIDUE ANP A 504 source : BC3 30) chain A residue 386 type sequence E description BINDING SITE FOR RESIDUE ANP A 504 source : BC3 31) chain A residue 387 type sequence G description BINDING SITE FOR RESIDUE ANP A 504 source : BC3 32) chain A residue 391 type sequence N description BINDING SITE FOR RESIDUE ANP A 504 source : BC3 33) chain A residue 393 type sequence Y description BINDING SITE FOR RESIDUE ANP A 504 source : BC3 34) chain A residue 415 type sequence M description BINDING SITE FOR RESIDUE ANP A 504 source : BC3 35) chain A residue 416 type sequence E description BINDING SITE FOR RESIDUE ANP A 504 source : BC3 36) chain A residue 417 type sequence L description BINDING SITE FOR RESIDUE ANP A 504 source : BC3 37) chain A residue 418 type sequence I description BINDING SITE FOR RESIDUE ANP A 504 source : BC3 38) chain A residue 442 type sequence E description BINDING SITE FOR RESIDUE ANP A 504 source : BC3 39) chain A residue 469 type sequence K description BINDING SITE FOR RESIDUE ANP A 504 source : BC3 40) chain B residue 1145 type sequence V description BINDING SITE FOR RESIDUE ANP B 1504 source : BC4 41) chain B residue 1146 type sequence E description BINDING SITE FOR RESIDUE ANP B 1504 source : BC4 42) chain B residue 1324 type sequence K description BINDING SITE FOR RESIDUE ANP B 1504 source : BC4 43) chain B residue 1380 type sequence V description BINDING SITE FOR RESIDUE ANP B 1504 source : BC4 44) chain B residue 1382 type sequence K description BINDING SITE FOR RESIDUE ANP B 1504 source : BC4 45) chain B residue 1386 type sequence E description BINDING SITE FOR RESIDUE ANP B 1504 source : BC4 46) chain B residue 1391 type sequence N description BINDING SITE FOR RESIDUE ANP B 1504 source : BC4 47) chain B residue 1393 type sequence Y description BINDING SITE FOR RESIDUE ANP B 1504 source : BC4 48) chain B residue 1415 type sequence M description BINDING SITE FOR RESIDUE ANP B 1504 source : BC4 49) chain B residue 1416 type sequence E description BINDING SITE FOR RESIDUE ANP B 1504 source : BC4 50) chain B residue 1417 type sequence L description BINDING SITE FOR RESIDUE ANP B 1504 source : BC4 51) chain B residue 1418 type sequence I description BINDING SITE FOR RESIDUE ANP B 1504 source : BC4 52) chain B residue 1442 type sequence E description BINDING SITE FOR RESIDUE ANP B 1504 source : BC4 53) chain B residue 1469 type sequence K description BINDING SITE FOR RESIDUE ANP B 1504 source : BC4 54) chain A residue 128 type sequence R description BINDING SITE FOR RESIDUE 3GC A 501 source : BC5 55) chain A residue 148 type sequence N description BINDING SITE FOR RESIDUE 3GC A 501 source : BC5 56) chain A residue 150 type sequence V description BINDING SITE FOR RESIDUE 3GC A 501 source : BC5 57) chain A residue 151 type sequence S description BINDING SITE FOR RESIDUE 3GC A 501 source : BC5 58) chain A residue 152 type sequence V description BINDING SITE FOR RESIDUE 3GC A 501 source : BC5 59) chain A residue 153 type sequence S description BINDING SITE FOR RESIDUE 3GC A 501 source : BC5 60) chain A residue 228 type sequence E description BINDING SITE FOR RESIDUE 3GC A 501 source : BC5 61) chain A residue 230 type sequence N description BINDING SITE FOR RESIDUE 3GC A 501 source : BC5 62) chain A residue 234 type sequence Q description BINDING SITE FOR RESIDUE 3GC A 501 source : BC5 63) chain A residue 285 type sequence R description BINDING SITE FOR RESIDUE 3GC A 501 source : BC5 64) chain A residue 288 type sequence Y description BINDING SITE FOR RESIDUE 3GC A 501 source : BC5 65) chain A residue 467 type sequence R description BINDING SITE FOR RESIDUE 3GC A 501 source : BC5 66) chain B residue 1128 type sequence R description BINDING SITE FOR RESIDUE 3GC B 1501 source : BC6 67) chain B residue 1150 type sequence V description BINDING SITE FOR RESIDUE 3GC B 1501 source : BC6 68) chain B residue 1151 type sequence S description BINDING SITE FOR RESIDUE 3GC B 1501 source : BC6 69) chain B residue 1152 type sequence V description BINDING SITE FOR RESIDUE 3GC B 1501 source : BC6 70) chain B residue 1153 type sequence S description BINDING SITE FOR RESIDUE 3GC B 1501 source : BC6 71) chain B residue 1228 type sequence E description BINDING SITE FOR RESIDUE 3GC B 1501 source : BC6 72) chain B residue 1230 type sequence N description BINDING SITE FOR RESIDUE 3GC B 1501 source : BC6 73) chain B residue 1234 type sequence Q description BINDING SITE FOR RESIDUE 3GC B 1501 source : BC6 74) chain B residue 1285 type sequence R description BINDING SITE FOR RESIDUE 3GC B 1501 source : BC6 75) chain B residue 1288 type sequence Y description BINDING SITE FOR RESIDUE 3GC B 1501 source : BC6 76) chain B residue 1467 type sequence R description BINDING SITE FOR RESIDUE 3GC B 1501 source : BC6 77) chain A residue 128 type BINDING sequence R description BINDING => ECO:0000269|PubMed:12467574 source Swiss-Prot : SWS_FT_FI1 78) chain A residue 234 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:12467574 source Swiss-Prot : SWS_FT_FI1 79) chain B residue 1128 type BINDING sequence R description BINDING => ECO:0000269|PubMed:12467574 source Swiss-Prot : SWS_FT_FI1 80) chain B residue 1234 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:12467574 source Swiss-Prot : SWS_FT_FI1 81) chain A residue 146 type BINDING sequence E description source Swiss-Prot : SWS_FT_FI2 82) chain A residue 442 type BINDING sequence E description source Swiss-Prot : SWS_FT_FI2 83) chain A residue 469 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI2 84) chain B residue 1146 type BINDING sequence E description source Swiss-Prot : SWS_FT_FI2 85) chain B residue 1150 type BINDING sequence V description source Swiss-Prot : SWS_FT_FI2 86) chain B residue 1228 type BINDING sequence E description source Swiss-Prot : SWS_FT_FI2 87) chain B residue 1285 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI2 88) chain B residue 1324 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI2 89) chain B residue 1382 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI2 90) chain B residue 1386 type BINDING sequence E description source Swiss-Prot : SWS_FT_FI2 91) chain B residue 1393 type BINDING sequence Y description source Swiss-Prot : SWS_FT_FI2 92) chain A residue 150 type BINDING sequence V description source Swiss-Prot : SWS_FT_FI2 93) chain B residue 1415 type BINDING sequence M description source Swiss-Prot : SWS_FT_FI2 94) chain B residue 1442 type BINDING sequence E description source Swiss-Prot : SWS_FT_FI2 95) chain B residue 1469 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI2 96) chain A residue 228 type BINDING sequence E description source Swiss-Prot : SWS_FT_FI2 97) chain A residue 285 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI2 98) chain A residue 324 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI2 99) chain A residue 382 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI2 100) chain A residue 386 type BINDING sequence E description source Swiss-Prot : SWS_FT_FI2 101) chain A residue 393 type BINDING sequence Y description source Swiss-Prot : SWS_FT_FI2 102) chain A residue 415 type BINDING sequence M description source Swiss-Prot : SWS_FT_FI2 103) chain A residue 148 type BINDING sequence N description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 104) chain A residue 467 type BINDING sequence R description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 105) chain A residue 475 type BINDING sequence E description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 106) chain A residue 478 type BINDING sequence V description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 107) chain B residue 1148 type BINDING sequence N description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 108) chain B residue 1467 type BINDING sequence R description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 109) chain B residue 1475 type BINDING sequence E description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 110) chain B residue 1478 type BINDING sequence V description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3

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