|
|
eF-site ID
|
1lz5-A |
|
PDB Code
|
1lz5 |
|
Chain
|
A |
|
click to enlarge
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Title
|
STRUCTURAL AND FUNCTIONAL ANALYSES OF THE ARG-GLY-ASP SEQUENCE INTRODUCED INTO HUMAN LYSOZYME |
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Classification
|
HYDROLASE(O-GLYCOSYL) |
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Compound
|
HUMAN LYSOZYME |
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Source
|
null (LYSC_HUMAN) |
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|
Sequence
|
A: |
KVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNT
RATNYNAGDRSTDYGIFQINSRYWCNDGKTPGAVRGDSNA
CHLSCSALLQDNIADAVACAKRVVRDPQGIRAWVAWRNRC
QNRDVRQYVQGCGV
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Description
|
(1) |
LYSOZYME (E.C.3.2.1.17) MUTANT WITH FOUR AMINO ACID RESIDUES (ARG 74A, GLY 74B, ASP 74C AND SER 74D) INSERTED BETWEEN VAL 74 AND ASN 75
|
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Functional site
|
|
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1)
|
chain |
A |
| residue |
80 |
| type |
|
| sequence |
S
|
| description |
BINDING SITE FOR RESIDUE CL A 131
|
| source |
: AC1
|
|
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2)
|
chain |
A |
| residue |
107 |
| type |
|
| sequence |
R
|
| description |
BINDING SITE FOR RESIDUE CL A 131
|
| source |
: AC1
|
|
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3)
|
chain |
A |
| residue |
27 |
| type |
|
| sequence |
N
|
| description |
BINDING SITE FOR RESIDUE CL A 132
|
| source |
: AC2
|
|
|
4)
|
chain |
A |
| residue |
66 |
| type |
|
| sequence |
N
|
| description |
BINDING SITE FOR RESIDUE CL A 132
|
| source |
: AC2
|
|
|
5)
|
chain |
A |
| residue |
80 |
| type |
|
| sequence |
S
|
| description |
BINDING SITE FOR RESIDUE CL A 132
|
| source |
: AC2
|
|
|
6)
|
chain |
A |
| residue |
77-95 |
| type |
prosite |
| sequence |
CHLSCSALLQDNIADAVAC
|
| description |
GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. ChlsCsaLlqdNIadavaC
|
| source |
prosite : PS00128
|
|
|
7)
|
chain |
A |
| residue |
35 |
| type |
ACT_SITE |
| sequence |
E
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
8)
|
chain |
A |
| residue |
53 |
| type |
ACT_SITE |
| sequence |
D
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|