eF-site ID 1lvc-C PDB Code 1lvc Chain C click to enlarge Title Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin and 2' deoxy, 3' anthraniloyl ATP Classification LYASE Compound calmodulin-sensitive adenylate cyclase Source (CALM_HUMAN) Sequence C:  RIDVLKGEKALKASGLVPEHADAFKKIARELNTYILFRPV NKLATNLIKSGVATKGLNVHGKSSDWGPVAGYIPFDQDLS KKHGQQLAVEKGNLENKKSITEHEGEIGKIPLKLDHLRIE ELKENGIILKGKKEIDNGKKYYLLESNNQVYEFRISDENN EVQYKTKEGKITVLGEKFNWRNIEVMAKNVEGVLKPLTAD YDLFALAPSLTEIKKQIPQKEWDKVVNTPNSLEKQKGVTN LLIKYGIERKPDSTKGTLSNWQKQMLDRLNEAVKYTGYTG GDVVNHGTEQDNEEFPEKDNEIFIINPEGEFILTKNWEMT GRFIEKNITGKDYLYYFNRSYNKIAPGNKAYIEWTDPITK AKINTIPTSAEFIKNLSSIRRSSNVGVYKDSGDKDEFAKK ESVKKIAGYLSDYYNSANHIFSQEKKRKISIFRGIQAYNE IENVLKSKQIAPEYKNYFQYLKERITNQVQLLLTHQKFKL LYKQLNFTENETDNFEVFQKIID Description Functional site 1) chain C residue 491 type sequence D description BINDING SITE FOR RESIDUE YB C 903 source : AC9 2) chain C residue 493 type sequence D description BINDING SITE FOR RESIDUE YB C 903 source : AC9 3) chain C residue 577 type sequence H description BINDING SITE FOR RESIDUE YB C 903 source : AC9 4) chain C residue 329 type sequence R description BINDING SITE FOR RESIDUE DOT C 1999 source : BC2 5) chain C residue 346 type sequence K description BINDING SITE FOR RESIDUE DOT C 1999 source : BC2 6) chain C residue 350 type sequence V description BINDING SITE FOR RESIDUE DOT C 1999 source : BC2 7) chain C residue 351 type sequence H description BINDING SITE FOR RESIDUE DOT C 1999 source : BC2 8) chain C residue 353 type sequence K description BINDING SITE FOR RESIDUE DOT C 1999 source : BC2 9) chain C residue 354 type sequence S description BINDING SITE FOR RESIDUE DOT C 1999 source : BC2 10) chain C residue 372 type sequence K description BINDING SITE FOR RESIDUE DOT C 1999 source : BC2 11) chain C residue 386 type sequence E description BINDING SITE FOR RESIDUE DOT C 1999 source : BC2 12) chain C residue 490 type sequence A description BINDING SITE FOR RESIDUE DOT C 1999 source : BC2 13) chain C residue 493 type sequence D description BINDING SITE FOR RESIDUE DOT C 1999 source : BC2 14) chain C residue 548 type sequence T description BINDING SITE FOR RESIDUE DOT C 1999 source : BC2 15) chain C residue 577 type sequence H description BINDING SITE FOR RESIDUE DOT C 1999 source : BC2 16) chain C residue 578 type sequence G description BINDING SITE FOR RESIDUE DOT C 1999 source : BC2 17) chain C residue 579 type sequence T description BINDING SITE FOR RESIDUE DOT C 1999 source : BC2 18) chain C residue 582 type sequence D description BINDING SITE FOR RESIDUE DOT C 1999 source : BC2 19) chain C residue 583 type sequence N description BINDING SITE FOR RESIDUE DOT C 1999 source : BC2 20) chain C residue 586 type sequence F description BINDING SITE FOR RESIDUE DOT C 1999 source : BC2

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