eF-site ID 1lvc-A PDB Code 1lvc Chain A click to enlarge Title Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin and 2' deoxy, 3' anthraniloyl ATP Classification LYASE Compound calmodulin-sensitive adenylate cyclase Source (CALM_HUMAN) Sequence A:  RIDVLKGEKALKASGLVPEHADAFKKIARELNTYILFRPV NKLATNLIKSGVATKGLNVHGKSSDWGPVAGYIPFDQDLS KKHGQQLAVEKGNLENKKSITEHEGEIGKIPLKLDHLRIE ELKENGIILKGKKEIDNGKKYYLLESNNQVYEFRISDENN EVQYKTKEGKITVLGEKFNWRNIEVMAKNVEGVLKPLTAD YDLFALAPSLTEIKKQIPQKEWDKVVNTPNSLEKQKGVTN LLIKYGIERKPDSTKGTLSNWQKQMLDRLNEAVKYTGYTG GDVVNHGTEQDNEEFPEKDNEIFIINPEGEFILTKNWEMT GRFIEKNITGKDYLYYFNRSYNKIAPGNKAYIEWTDPITK AKINTIPTSAEFIKNLSSIRRSSSVKKIAGYLSDYYNSAN HIFSQEKKRKISIFRGIQAYNEIENVLKSKQIAPEYKNYF QYLKERITNQVQLLLTHQKFKLLYKQLNFTENETDNFEVF QKIID Description Functional site 1) chain A residue 491 type sequence D description BINDING SITE FOR RESIDUE YB A 901 source : AC7 2) chain A residue 493 type sequence D description BINDING SITE FOR RESIDUE YB A 901 source : AC7 3) chain A residue 577 type sequence H description BINDING SITE FOR RESIDUE YB A 901 source : AC7 4) chain A residue 329 type sequence R description BINDING SITE FOR RESIDUE DOT A 999 source : BC1 5) chain A residue 346 type sequence K description BINDING SITE FOR RESIDUE DOT A 999 source : BC1 6) chain A residue 350 type sequence V description BINDING SITE FOR RESIDUE DOT A 999 source : BC1 7) chain A residue 351 type sequence H description BINDING SITE FOR RESIDUE DOT A 999 source : BC1 8) chain A residue 353 type sequence K description BINDING SITE FOR RESIDUE DOT A 999 source : BC1 9) chain A residue 354 type sequence S description BINDING SITE FOR RESIDUE DOT A 999 source : BC1 10) chain A residue 372 type sequence K description BINDING SITE FOR RESIDUE DOT A 999 source : BC1 11) chain A residue 382 type sequence K description BINDING SITE FOR RESIDUE DOT A 999 source : BC1 12) chain A residue 386 type sequence E description BINDING SITE FOR RESIDUE DOT A 999 source : BC1 13) chain A residue 490 type sequence A description BINDING SITE FOR RESIDUE DOT A 999 source : BC1 14) chain A residue 493 type sequence D description BINDING SITE FOR RESIDUE DOT A 999 source : BC1 15) chain A residue 577 type sequence H description BINDING SITE FOR RESIDUE DOT A 999 source : BC1 16) chain A residue 578 type sequence G description BINDING SITE FOR RESIDUE DOT A 999 source : BC1 17) chain A residue 579 type sequence T description BINDING SITE FOR RESIDUE DOT A 999 source : BC1 18) chain A residue 583 type sequence N description BINDING SITE FOR RESIDUE DOT A 999 source : BC1 19) chain A residue 586 type sequence F description BINDING SITE FOR RESIDUE DOT A 999 source : BC1

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