|
|
eF-site ID
|
1lsn-A |
|
PDB Code
|
1lsn |
|
Chain
|
A |
|
click to enlarge
|
|
|
Title
|
THERMAL STABILITY DETERMINANTS OF CHICKEN EGG-WHITE LYSOZYME CORE MUTANTS: HYDROPHOBICITY, PACKING VOLUME AND CONSERVED BURIED WATER MOLECULES |
|
Classification
|
HYDROLASE(O-GLYCOSYL) |
|
Compound
|
HEN EGG WHITE LYSOZYME |
|
Source
|
null (LYSC_CHICK) |
|
|
Sequence
|
A: |
KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNT
QATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPC
SALLSSDITAAVNCAKKIVSNGNGMNAWVAWRNRCKGTDV
QAWIRGCRL
|
|
|
Description
|
(1) |
LYSOZYME (E.C.3.2.1.17) MUTANT WITH SER 91 REPLACED BY ALA (S91A)
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
35 |
| type |
catalytic |
| sequence |
E
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
2)
|
chain |
A |
| residue |
46 |
| type |
catalytic |
| sequence |
N
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
3)
|
chain |
A |
| residue |
48 |
| type |
catalytic |
| sequence |
D
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
4)
|
chain |
A |
| residue |
50 |
| type |
catalytic |
| sequence |
S
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
5)
|
chain |
A |
| residue |
52 |
| type |
catalytic |
| sequence |
D
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
6)
|
chain |
A |
| residue |
59 |
| type |
catalytic |
| sequence |
N
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
7)
|
chain |
A |
| residue |
76-94 |
| type |
prosite |
| sequence |
CNIPCSALLSSDITAAVNC
|
| description |
GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CnipCsaLlssDItaavnC
|
| source |
prosite : PS00128
|
|
|
8)
|
chain |
A |
| residue |
35 |
| type |
ACT_SITE |
| sequence |
E
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
9)
|
chain |
A |
| residue |
52 |
| type |
ACT_SITE |
| sequence |
D
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
10)
|
chain |
A |
| residue |
101 |
| type |
BINDING |
| sequence |
N
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|