eF-site ID 1lpg-B PDB Code 1lpg Chain B click to enlarge Title CRYSTAL STRUCTURE OF FXA IN COMPLEX WITH 79. Classification HYDROLASE Compound Blood coagulation factor Xa Source ORGANISM_COMMON: human; ORGANISM_SCIENTIFIC: Homo sapiens; Sequence B:  IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTA AHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRF TKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLM TQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSS SFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVT GIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT Description (1)  Coagulation factor X (E.C.3.4.21.6) Functional site 1) chain B residue 70 type sequence D description BINDING SITE FOR RESIDUE CA B 1 source : AC1 2) chain B residue 72 type sequence N description BINDING SITE FOR RESIDUE CA B 1 source : AC1 3) chain B residue 75 type sequence Q description BINDING SITE FOR RESIDUE CA B 1 source : AC1 4) chain B residue 97 type sequence E description BINDING SITE FOR RESIDUE IMA B 301 source : AC2 5) chain B residue 98 type sequence T description BINDING SITE FOR RESIDUE IMA B 301 source : AC2 6) chain B residue 99 type sequence Y description BINDING SITE FOR RESIDUE IMA B 301 source : AC2 7) chain B residue 143 type sequence R description BINDING SITE FOR RESIDUE IMA B 301 source : AC2 8) chain B residue 147 type sequence E description BINDING SITE FOR RESIDUE IMA B 301 source : AC2 9) chain B residue 148 type sequence K description BINDING SITE FOR RESIDUE IMA B 301 source : AC2 10) chain B residue 149 type sequence G description BINDING SITE FOR RESIDUE IMA B 301 source : AC2 11) chain B residue 174 type sequence F description BINDING SITE FOR RESIDUE IMA B 301 source : AC2 12) chain B residue 189 type sequence D description BINDING SITE FOR RESIDUE IMA B 301 source : AC2 13) chain B residue 190 type sequence A description BINDING SITE FOR RESIDUE IMA B 301 source : AC2 14) chain B residue 191 type sequence C description BINDING SITE FOR RESIDUE IMA B 301 source : AC2 15) chain B residue 192 type sequence Q description BINDING SITE FOR RESIDUE IMA B 301 source : AC2 16) chain B residue 195 type sequence S description BINDING SITE FOR RESIDUE IMA B 301 source : AC2 17) chain B residue 215 type sequence W description BINDING SITE FOR RESIDUE IMA B 301 source : AC2 18) chain B residue 216 type sequence G description BINDING SITE FOR RESIDUE IMA B 301 source : AC2 19) chain B residue 219 type sequence G description BINDING SITE FOR RESIDUE IMA B 301 source : AC2 20) chain B residue 220 type sequence C description BINDING SITE FOR RESIDUE IMA B 301 source : AC2 21) chain B residue 226 type sequence G description BINDING SITE FOR RESIDUE IMA B 301 source : AC2 22) chain B residue 57 type ACT_SITE sequence H description Charge relay system source Swiss-Prot : SWS_FT_FI1 23) chain B residue 102 type ACT_SITE sequence D description Charge relay system source Swiss-Prot : SWS_FT_FI1 24) chain B residue 195 type ACT_SITE sequence S description Charge relay system source Swiss-Prot : SWS_FT_FI1 25) chain B residue 53-58 type prosite sequence LTAAHC description TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC source prosite : PS00134 26) chain B residue 189-200 type prosite sequence DACQGDSGGPHV description TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAcqGDSGGPHV source prosite : PS00135

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