eF-site ID 1kpm-B PDB Code 1kpm Chain B click to enlarge Title First Structural Evidence of a Specific Inhibition of Phospholipase A2 by Vitamin E and its Implications in Inflammation: Crystal Structure of the Complex Formed between Phospholipase A2 and Vitamin E at 1.8 A Resolution. Classification HYDROLASE Compound Phospholipase A2 Source ORGANISM_SCIENTIFIC: Daboia russellii pulchella; Sequence B:  SLLEFGKMILEETGKLAIPSYSSYGCYCGWGGKGTPKDAT DRCCFVHDCCYGNLPDCNPKSDRYKYKRVNGAIVCEKGTS CENRICECDKAAAICFRQNLNTYSKKYMLYPDFLCKGELK C Description Functional site 1) chain B residue 54 type sequence N description BINDING SITE FOR RESIDUE VIT A 401 source : AC1 2) chain B residue 133 type sequence C description BINDING SITE FOR RESIDUE VIT A 401 source : AC1 3) chain B residue 11 type sequence E description BINDING SITE FOR RESIDUE ACY B 501 source : AC2 4) chain B residue 77 type sequence R description BINDING SITE FOR RESIDUE ACY B 501 source : AC2 5) chain B residue 107 type sequence R description BINDING SITE FOR RESIDUE ACY B 501 source : AC2 6) chain B residue 107 type sequence R description BINDING SITE FOR RESIDUE ACY B 502 source : AC3 7) chain B residue 108 type sequence Q description BINDING SITE FOR RESIDUE ACY B 502 source : AC3 8) chain B residue 89 type sequence T description BINDING SITE FOR RESIDUE ACY B 503 source : AC4 9) chain B residue 90 type sequence S description BINDING SITE FOR RESIDUE ACY B 503 source : AC4 10) chain B residue 48 type ACT_SITE sequence H description ACT_SITE => ECO:0000250|UniProtKB:P14418 source Swiss-Prot : SWS_FT_FI1 11) chain B residue 99 type ACT_SITE sequence D description ACT_SITE => ECO:0000250|UniProtKB:P14418 source Swiss-Prot : SWS_FT_FI1 12) chain B residue 28 type BINDING sequence Y description BINDING => ECO:0000269|Ref.12, ECO:0007744|PDB:1TGM source Swiss-Prot : SWS_FT_FI2 13) chain B residue 30 type BINDING sequence G description BINDING => ECO:0000269|Ref.12, ECO:0007744|PDB:1TGM source Swiss-Prot : SWS_FT_FI2 14) chain B residue 32 type BINDING sequence G description BINDING => ECO:0000269|Ref.12, ECO:0007744|PDB:1TGM source Swiss-Prot : SWS_FT_FI2 15) chain B residue 49 type BINDING sequence D description BINDING => ECO:0000269|Ref.12, ECO:0007744|PDB:1TGM source Swiss-Prot : SWS_FT_FI2

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