eF-site ID 1kie-A PDB Code 1kie Chain A click to enlarge Title Inosine-adenosine-guanosine preferring nucleoside hydrolase from Trypanosoma vivax: Asp10Ala mutant in complex with 3-deaza-adenosine Classification HYDROLASE Compound inosine-adenosine-guanosine preferring nucleoside hydrolase Source Trypanosoma vivax (Q9GPQ4_TRYVI) Sequence A:  SAKNVVLDHAGNLDDFVAMVLLASNTEKVRLIGALCTDAD CFVENGFNVTGKIMCLMHNNMNLPLFPIGKSAATAVNPFP KEWRCLAKNMDDMPILNIPENVELWDKIKAENEKYEGQQL LADLVMNSEEKVTICVTGPLSNVAWCIDKYGEKFTSKVEE CVIMGGAVDVRGNVFLPSTDGTAEWNIYWDPASAKTVFGC PGLRRIMFSLDSTNTVPVRSPYVQRFGEQTNFLLSILVGT MWAMCYAWDALTAAYVVDQKVANVDPVPIDVVVDKQPNEG ATVRTDAENYPLTFVARNPEAEFFLDMLLRSARAC Description Functional site 1) chain A residue 15 type sequence D description BINDING SITE FOR RESIDUE CA A 328 source : AC1 2) chain A residue 137 type sequence T description BINDING SITE FOR RESIDUE CA A 328 source : AC1 3) chain A residue 261 type sequence D description BINDING SITE FOR RESIDUE CA A 328 source : AC1 4) chain A residue 44 type sequence E description BINDING SITE FOR RESIDUE NI A 701 source : AC3 5) chain A residue 113 type sequence E description BINDING SITE FOR RESIDUE NI A 701 source : AC3 6) chain A residue 14 type sequence D description BINDING SITE FOR RESIDUE AD3 A 801 source : AC4 7) chain A residue 40 type sequence D description BINDING SITE FOR RESIDUE AD3 A 801 source : AC4 8) chain A residue 137 type sequence T description BINDING SITE FOR RESIDUE AD3 A 801 source : AC4 9) chain A residue 164 type sequence M description BINDING SITE FOR RESIDUE AD3 A 801 source : AC4 10) chain A residue 173 type sequence N description BINDING SITE FOR RESIDUE AD3 A 801 source : AC4 11) chain A residue 184 type sequence E description BINDING SITE FOR RESIDUE AD3 A 801 source : AC4 12) chain A residue 186 type sequence N description BINDING SITE FOR RESIDUE AD3 A 801 source : AC4 13) chain A residue 260 type sequence W description BINDING SITE FOR RESIDUE AD3 A 801 source : AC4 14) chain A residue 261 type sequence D description BINDING SITE FOR RESIDUE AD3 A 801 source : AC4

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