eF-site ID 1ki8-B PDB Code 1ki8 Chain B click to enlarge Title CRYSTAL STRUCTURE OF THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE I COMPLEXED WITH 5-BROMOVINYLDEOXYURIDINE Classification PHOSPHOTRANSFERASE Compound THYMIDINE KINASE Source Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) (KITH_HSV11) Sequence B:  MPTLLRVYIDGPHGMGKTTTTQLLVALGDIVYVPEPMTYW RVLGASETIANIYTTQHRLDQGEISAGDAAVVMTSAQITM GMPYAVTDAVLAPHIGGEAGSSAPPPALTLIFDRHPIAAL LCYPAARYLMGSMTPQAVLAFVALIPPTLPGTNIVLGALP EDRHIDRLAKRQRPGERLDLAMLAAIRRVYGLLANTVRYL QCGGSWREDWGQLSNAGPRPHIGDTLFTLFRAPELLAPNG DLYNVFAWALDVLAKRLRSMHVFILDYDQSPAGCRDALLQ LTSGMVQTHVTTPGSIPTICDLARTFAREMGE Description Functional site 1) chain B residue 59 type sequence G description BINDING SITE FOR RESIDUE SO4 B 4 source : AC2 2) chain B residue 60 type sequence M description BINDING SITE FOR RESIDUE SO4 B 4 source : AC2 3) chain B residue 61 type sequence G description BINDING SITE FOR RESIDUE SO4 B 4 source : AC2 4) chain B residue 62 type sequence K description BINDING SITE FOR RESIDUE SO4 B 4 source : AC2 5) chain B residue 63 type sequence T description BINDING SITE FOR RESIDUE SO4 B 4 source : AC2 6) chain B residue 58 type sequence H description BINDING SITE FOR RESIDUE BVD B 2 source : AC4 7) chain B residue 83 type sequence E description BINDING SITE FOR RESIDUE BVD B 2 source : AC4 8) chain B residue 100 type sequence I description BINDING SITE FOR RESIDUE BVD B 2 source : AC4 9) chain B residue 101 type sequence Y description BINDING SITE FOR RESIDUE BVD B 2 source : AC4 10) chain B residue 125 type sequence Q description BINDING SITE FOR RESIDUE BVD B 2 source : AC4 11) chain B residue 128 type sequence M description BINDING SITE FOR RESIDUE BVD B 2 source : AC4 12) chain B residue 132 type sequence Y description BINDING SITE FOR RESIDUE BVD B 2 source : AC4 13) chain B residue 167 type sequence A description BINDING SITE FOR RESIDUE BVD B 2 source : AC4 14) chain B residue 168 type sequence A description BINDING SITE FOR RESIDUE BVD B 2 source : AC4 15) chain B residue 172 type sequence Y description BINDING SITE FOR RESIDUE BVD B 2 source : AC4 16) chain B residue 222 type sequence R description BINDING SITE FOR RESIDUE BVD B 2 source : AC4 17) chain B residue 225 type sequence E description BINDING SITE FOR RESIDUE BVD B 2 source : AC4 18) chain B residue 62 type catalytic sequence K description 588 source MCSA : MCSA2 19) chain B residue 83 type catalytic sequence E description 588 source MCSA : MCSA2 20) chain B residue 162 type catalytic sequence D description 588 source MCSA : MCSA2 21) chain B residue 163 type catalytic sequence R description 588 source MCSA : MCSA2 22) chain B residue 220 type catalytic sequence R description 588 source MCSA : MCSA2 23) chain B residue 222 type catalytic sequence R description 588 source MCSA : MCSA2 24) chain B residue 225 type catalytic sequence E description 588 source MCSA : MCSA2 25) chain B residue 83 type ACT_SITE sequence E description Proton acceptor => ECO:0000255|HAMAP-Rule:MF_04029 source Swiss-Prot : SWS_FT_FI1 26) chain B residue 222 type BINDING sequence R description BINDING => ECO:0000255|HAMAP-Rule:MF_04029 source Swiss-Prot : SWS_FT_FI2 27) chain B residue 56 type BINDING sequence G description BINDING => ECO:0000255|HAMAP-Rule:MF_04029 source Swiss-Prot : SWS_FT_FI2 28) chain B residue 101 type BINDING sequence Y description BINDING => ECO:0000255|HAMAP-Rule:MF_04029 source Swiss-Prot : SWS_FT_FI2 29) chain B residue 125 type BINDING sequence Q description BINDING => ECO:0000255|HAMAP-Rule:MF_04029 source Swiss-Prot : SWS_FT_FI2 30) chain B residue 216 type BINDING sequence R description BINDING => ECO:0000255|HAMAP-Rule:MF_04029 source Swiss-Prot : SWS_FT_FI2

Display surface Download Links