eF-site ID 1ki1-A
PDB Code 1ki1
Chain A

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Title Guanine Nucleotide Exchange Region of Intersectin in Complex with Cdc42
Classification SIGNALING PROTEIN
Compound G25K GTP-binding protein, placental isoform
Source null (ITSN1_HUMAN)
Sequence A:  MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNY
AVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLV
CFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR
DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSAL
TQKGLKNVFDEAILAALE
Description


Functional site

1) chain A
residue 11
type
sequence D
description BINDING SITE FOR RESIDUE SO4 A 4001
source : AC1

2) chain A
residue 12
type
sequence G
description BINDING SITE FOR RESIDUE SO4 A 4001
source : AC1

3) chain A
residue 13
type
sequence A
description BINDING SITE FOR RESIDUE SO4 A 4001
source : AC1

4) chain A
residue 14
type
sequence V
description BINDING SITE FOR RESIDUE SO4 A 4001
source : AC1

5) chain A
residue 15
type
sequence G
description BINDING SITE FOR RESIDUE SO4 A 4001
source : AC1

6) chain A
residue 16
type
sequence K
description BINDING SITE FOR RESIDUE SO4 A 4001
source : AC1

7) chain A
residue 17
type
sequence T
description BINDING SITE FOR RESIDUE SO4 A 4001
source : AC1

8) chain A
residue 35
type CARBOHYD
sequence T
description (Microbial infection) O-linked (Glc) threonine; by C.difficile toxins TcdA and TcdB; alternate => ECO:0000269|PubMed:24905543, ECO:0000269|PubMed:7775453, ECO:0000269|PubMed:7777059
source Swiss-Prot : SWS_FT_FI9

9) chain A
residue 57
type BINDING
sequence D
description BINDING => ECO:0000250
source Swiss-Prot : SWS_FT_FI2

10) chain A
residue 32
type MOD_RES
sequence Y
description (Microbial infection) O-AMP-tyrosine; by Haemophilus IbpA; alternate => ECO:0000269|PubMed:19362538, ECO:0000269|PubMed:20622875
source Swiss-Prot : SWS_FT_FI3

11) chain A
residue 35
type MOD_RES
sequence T
description (Microbial infection) O-AMP-threonine; by Vibrio VopS => ECO:0000269|PubMed:19039103
source Swiss-Prot : SWS_FT_FI4

12) chain A
residue 64
type MOD_RES
sequence Y
description Phosphotyrosine; by SRC => ECO:0000269|PubMed:14506284
source Swiss-Prot : SWS_FT_FI5

13) chain A
residue 32
type CARBOHYD
sequence Y
description (Microbial infection) O-linked (GlcNAc) tyrosine; by Photorhabdus PAU_02230; alternate => ECO:0000269|PubMed:24141704
source Swiss-Prot : SWS_FT_FI8

14) chain A
residue 10
type BINDING
sequence G
description
source Swiss-Prot : SWS_FT_FI1

15) chain A
residue 115
type BINDING
sequence T
description
source Swiss-Prot : SWS_FT_FI1


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