eF-site ID 1kfe-AB PDB Code 1kfe Chain A, B click to enlarge Title CRYSTAL STRUCTURE OF ALPHAT183V MUTANT OF TRYPTOPHAN SYNTHASE FROM SALMONELLA TYPHIMURIUM WITH L-Ser Bound To The Beta Site Classification LYASE Compound TRYPTOPHAN SYNTHASE ALPHA CHAIN Source Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (TRPB_SALTY) Sequence A:  MERYENLFAQLNDRREGAFVPFVTLGDPGIEQSLKIIDTL IDAGADALELGVPFSDPLADGPTIQNANLRAFAAGVTPAQ CFEMLAIIREKHPTIPIGLLMYANLVFNNGIDAFYARCEQ VGVDSVLVADVPVEESAPFRQAALRHNIAPIFICPPNADD DLLRQVASYGRGYTYLLHHLIEKLKEYHAAPALQGFGISS PEQVSAAVRAGAAGAISGSAIVKIIEKNLASPKQMLAELR SFVSAMKAASRA B:  TTLLNPYFGEFGGMYVPQILMPALNQLEEAFVSAQKDPEF QAQFADLLKNYAGRPTALTKCQNITAGTRTTLYLKREDLL HGGAHKTNQVLGQALLAKRMGKSEIIAETGAGQHGVASAL ASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS GSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIV REFQRMIGEETKAQILDKEGRLPDAVIACVGGGSNAIGMF ADFINDTSVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFG MKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGR ADYVSITDDEALEAFKTLCRHEGIIPALESSHALAHALKM MREQPEKEQLLVVNLSGRGDKDIFTVHDILKARG Description Functional site 1) chain B residue 232 type sequence G description BINDING SITE FOR RESIDUE NA B 555 source : AC1 2) chain B residue 306 type sequence F description BINDING SITE FOR RESIDUE NA B 555 source : AC1 3) chain B residue 308 type sequence S description BINDING SITE FOR RESIDUE NA B 555 source : AC1 4) chain B residue 85 type sequence A description BINDING SITE FOR RESIDUE PLS B 550 source : AC2 5) chain B residue 86 type sequence H description BINDING SITE FOR RESIDUE PLS B 550 source : AC2 6) chain B residue 87 type sequence K description BINDING SITE FOR RESIDUE PLS B 550 source : AC2 7) chain B residue 110 type sequence T description BINDING SITE FOR RESIDUE PLS B 550 source : AC2 8) chain B residue 111 type sequence G description BINDING SITE FOR RESIDUE PLS B 550 source : AC2 9) chain B residue 112 type sequence A description BINDING SITE FOR RESIDUE PLS B 550 source : AC2 10) chain B residue 114 type sequence Q description BINDING SITE FOR RESIDUE PLS B 550 source : AC2 11) chain B residue 115 type sequence H description BINDING SITE FOR RESIDUE PLS B 550 source : AC2 12) chain B residue 190 type sequence T description BINDING SITE FOR RESIDUE PLS B 550 source : AC2 13) chain B residue 230 type sequence C description BINDING SITE FOR RESIDUE PLS B 550 source : AC2 14) chain B residue 232 type sequence G description BINDING SITE FOR RESIDUE PLS B 550 source : AC2 15) chain B residue 233 type sequence G description BINDING SITE FOR RESIDUE PLS B 550 source : AC2 16) chain B residue 234 type sequence G description BINDING SITE FOR RESIDUE PLS B 550 source : AC2 17) chain B residue 235 type sequence S description BINDING SITE FOR RESIDUE PLS B 550 source : AC2 18) chain B residue 236 type sequence N description BINDING SITE FOR RESIDUE PLS B 550 source : AC2 19) chain B residue 302 type sequence A description BINDING SITE FOR RESIDUE PLS B 550 source : AC2 20) chain B residue 303 type sequence G description BINDING SITE FOR RESIDUE PLS B 550 source : AC2 21) chain B residue 305 type sequence D description BINDING SITE FOR RESIDUE PLS B 550 source : AC2 22) chain B residue 350 type sequence E description BINDING SITE FOR RESIDUE PLS B 550 source : AC2 23) chain B residue 377 type sequence S description BINDING SITE FOR RESIDUE PLS B 550 source : AC2 24) chain B residue 87 type catalytic sequence K description 383 source MCSA : MCSA1 25) chain B residue 109 type catalytic sequence E description 383 source MCSA : MCSA1 26) chain B residue 377 type catalytic sequence S description 383 source MCSA : MCSA1 27) chain B residue 87 type MOD_RES sequence K description N6-(pyridoxal phosphate)lysine source Swiss-Prot : SWS_FT_FI1 28) chain A residue 60 type MOD_RES sequence D description N6-(pyridoxal phosphate)lysine source Swiss-Prot : SWS_FT_FI1 29) chain A residue 48-61 type prosite sequence LELGVPFSDPLADG description TRP_SYNTHASE_ALPHA Tryptophan synthase alpha chain signature. LELGvPFSDPLADG source prosite : PS00167 30) chain B residue 80-94 type prosite sequence LLHGGAHKTNQVLGQ description TRP_SYNTHASE_BETA Tryptophan synthase beta chain pyridoxal-phosphate attachment site. LlHgGAHKtNqvLgQ source prosite : PS00168

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