eF-site ID 1k90-A PDB Code 1k90 Chain A click to enlarge Title Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin and 3' deoxy-ATP Classification TOXIN,LYASE/METAL BINDING PROTEIN Compound CALMODULIN-SENSITIVE ADENYLATE CYCLASE Source (CALM_HUMAN) Sequence A:  RIDVLKGEKALKASGLVPEHADAFKKIARELNTYILFRPV NKLATNLIKSGVATKGLNVHGKSSDWGPVAGYIPFDQDLS KKHGQQLAVEKGNLENKKSITEHEGEIGKIPLKLDHLRIE ELKENGIILKGKKEIDNGKKYYLLESNNQVYEFRISDENN EVQYKTKEGKITVLGEKFNWRNIEVMAKNVEGVLKPLTAD YDLFALAPSLTEIKKQIPQKEWDKVVNTPNSLEKQKGVTN LLIKYGIERKPDSTKGTLSNWQKQMLDRLNEAVKYTGYTG GDVVNHGTEQDNEEFPEKDNEIFIINPEGEFILTKNWEMT GRFIEKNITGKDYLYYFNRSYNKIAPGNKAYIEWTDPITK AKINTIPTSAEFIKNLSSIRRSSSVKKIAGYLSDYYNSAN HIFSQEKKRKISIFRGIQAYNEIENVLKSKQIAPEYKNYF QYLKERITNQVQLLLTHQKFKLLYKQLNFTENETDNFEVF QKIID Description Functional site 1) chain A residue 491 type sequence D description BINDING SITE FOR RESIDUE YB A 901 source : AC3 2) chain A residue 493 type sequence D description BINDING SITE FOR RESIDUE YB A 901 source : AC3 3) chain A residue 577 type sequence H description BINDING SITE FOR RESIDUE YB A 901 source : AC3 4) chain A residue 329 type sequence R description BINDING SITE FOR RESIDUE 3AT A 902 source : BC1 5) chain A residue 346 type sequence K description BINDING SITE FOR RESIDUE 3AT A 902 source : BC1 6) chain A residue 351 type sequence H description BINDING SITE FOR RESIDUE 3AT A 902 source : BC1 7) chain A residue 354 type sequence S description BINDING SITE FOR RESIDUE 3AT A 902 source : BC1 8) chain A residue 372 type sequence K description BINDING SITE FOR RESIDUE 3AT A 902 source : BC1 9) chain A residue 491 type sequence D description BINDING SITE FOR RESIDUE 3AT A 902 source : BC1 10) chain A residue 493 type sequence D description BINDING SITE FOR RESIDUE 3AT A 902 source : BC1 11) chain A residue 547 type sequence G description BINDING SITE FOR RESIDUE 3AT A 902 source : BC1 12) chain A residue 548 type sequence T description BINDING SITE FOR RESIDUE 3AT A 902 source : BC1 13) chain A residue 577 type sequence H description BINDING SITE FOR RESIDUE 3AT A 902 source : BC1 14) chain A residue 578 type sequence G description BINDING SITE FOR RESIDUE 3AT A 902 source : BC1 15) chain A residue 579 type sequence T description BINDING SITE FOR RESIDUE 3AT A 902 source : BC1 16) chain A residue 583 type sequence N description BINDING SITE FOR RESIDUE 3AT A 902 source : BC1

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