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eF-site ID
|
1k6o-ABCDE |
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PDB Code
|
1k6o |
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Chain
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A, B, C, D, E |
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click to enlarge
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Title
|
Crystal Structure of a Ternary SAP-1/SRF/c-fos SRE DNA Complex |
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Classification
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TRANSCRIPTION/DNA |
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Compound
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5'-D(*CP*AP*CP*AP*GP*GP*AP*TP*GP*TP*CP*CP*AP*TP*AP*TP*TP*AP*GP*GP*AP*CP*A)-3' |
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Source
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Homo sapiens (Human) (1K6O) |
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Sequence
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A: |
SAITLWQFLLQLLQKPQNKHMICWTSNDGQFKLLQAEEVA
RLWGIRKNKPNMNYDKLSRALRYYYVKNIIKKVNGQKFVY
KFVSYPEIL
|
| B: |
GKKTRGRVKIKMEFIDNKLRRYTTFSKRKTGIMKKAYELS
TLTGTQVLLLVASETGHVYTFATRKLQPMITSETGKALIQ
TCLNS
|
| C: |
KKTRGRVKIKMEFIDNKLRRYTTFSKRKTGIMKKAYELST
LTGTQVLLLVASETGHVYTFATRKLQPMITSETGKALIQT
CLNS
|
| D: |
CACAGGATGTCCATATTAGGACA
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| E: |
TGTCCTAATATGGACATCCTGTG
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Description
|
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Functional site
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|
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1)
|
chain |
B |
| residue |
143-197 |
| type |
prosite |
| sequence |
RVKIKMEFIDNKLRRYTTFSKRKTGIMKKAYELSTLTGTQ
VLLLVASETGHVYTF
|
| description |
MADS_BOX_1 MADS-box domain signature. RvKikmefIdNklrRytTFsKRKtgImKKAyELStLtgtqVlLLVasetghVytF
|
| source |
prosite : PS00350
|
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2)
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chain |
A |
| residue |
307-315 |
| type |
prosite |
| sequence |
LWQFLLQLL
|
| description |
ETS_DOMAIN_1 Ets-domain signature 1. LWQFLLQLL
|
| source |
prosite : PS00345
|
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3)
|
chain |
A |
| residue |
351-366 |
| type |
prosite |
| sequence |
KPNMNYDKLSRALRYY
|
| description |
ETS_DOMAIN_2 Ets-domain signature 2. KpnMnYDkLSRALRyY
|
| source |
prosite : PS00346
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