|
|
eF-site ID
|
1k2d-ABP |
|
PDB Code
|
1k2d |
|
Chain
|
A, B, P |
|
click to enlarge
|
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Title
|
Crystal structure of the autoimmune MHC class II I-Au complexed with myelin basic protein 1-11 at 2.2A |
|
Classification
|
IMMUNE SYSTEM |
|
Compound
|
H-2 class II histocompatibility antigen, A-U alpha chain |
|
Source
|
(XP_040888) |
|
|
Sequence
|
A: |
IEADHVGSYGIVVYQSPGDIGQYTFEFDGDELFYVDLDKK
ETIWMLPEFAQLRSFDPQGGLQNIATGKHNLGVLTKRSNS
TPATNEAPQATVFPKSPVLLGQPNTLICFVDNIFPPVINI
TWLRNSKSVADGVYETSFFVNRDYSFHKLSYLTFIPSDDD
IYDCKVEHWGLEEPVLKHWEPE
|
| B: |
RHFVVQFQPFCYFTNGTQRIRYVTRYIYNREEYLRFDSDV
GEYRAVTELGRPDAEYYNKQYLERTRAELDTVCRYNYEET
EVPTSLRRLEQPNVVISLSRTEALNHHNTLVCSVTDFYPA
KIKVRWFRNGQEETVGVSSTQLIRNGDWTFQVLVMLEMTP
RRGEVYTCHVEHPSLKSPITVEWRA
|
| P: |
SRGGASQYRPSQ
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
161-167 |
| type |
prosite |
| sequence |
YDCKVEH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YDCKVEH
|
| source |
prosite : PS00290
|
|
|
2)
|
chain |
B |
| residue |
171-177 |
| type |
prosite |
| sequence |
YTCHVEH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YDCKVEH
|
| source |
prosite : PS00290
|
|
|
3)
|
chain |
P |
| residue |
7 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0000250|UniProtKB:P02687
|
| source |
Swiss-Prot : SWS_FT_FI1
|
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|
|