|
|
eF-site ID
|
1jsu-C |
|
PDB Code
|
1jsu |
|
Chain
|
C |
|
click to enlarge
|
|
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Title
|
P27(KIP1)/CYCLIN A/CDK2 COMPLEX |
|
Classification
|
COMPLEX (TRANSFERASE/CYCLIN/INHIBITOR) |
|
Compound
|
CYCLIN-DEPENDENT KINASE-2 |
|
Source
|
null (CDN1B_HUMAN) |
|
|
Sequence
|
C: |
KPSACRNLFGPVDHEELTRDLEKHCRDMEEASQRKWNFDF
QNHKPLEGKYEWQEVEKGSLPEFYYRPPR
|
|
|
Description
|
(1) |
CYCLIN-DEPENDENT KINASE-2, CYCLIN A, P27
|
|
Functional site
|
|
|
1)
|
chain |
C |
| residue |
74 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Phosphotyrosine; by SRC => ECO:0000269|PubMed:17254967
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
C |
| residue |
88 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Phosphotyrosine; by ABL, LYN, SRC and JAK2 => ECO:0000269|PubMed:16195327, ECO:0000269|PubMed:17254966, ECO:0000269|PubMed:17254967, ECO:0000269|PubMed:21423214
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
3)
|
chain |
C |
| residue |
89 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Phosphotyrosine => ECO:0000269|PubMed:16195327
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|