|
|
eF-site ID
|
1jsp_17-A |
|
PDB Code
|
1jsp |
|
Model
|
17 |
|
Chain
|
A |
|
click to enlarge
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|
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Title
|
NMR Structure of CBP Bromodomain in complex with p53 peptide |
|
Classification
|
DNA BINDING PROTEIN |
|
Compound
|
tumor protein p53 |
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Source
|
Homo sapiens (Human) (CBP_HUMAN) |
|
|
Sequence
|
A: |
SHLKSKKGQSTSRHKXLMFK
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
381 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0000269|PubMed:29474172, ECO:0007744|PubMed:19608861
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
2)
|
chain |
A |
| residue |
370 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-methyllysine; by SMYD2; alternate => ECO:0000269|PubMed:17108971, ECO:0000269|PubMed:22864287
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
A |
| residue |
372 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-methyllysine; by SETD7 => ECO:0000269|PubMed:15525938, ECO:0000269|PubMed:16415881
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
A |
| residue |
373 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine; alternate => ECO:0000269|PubMed:10656795
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
5)
|
chain |
A |
| residue |
382 |
| type |
MOD_RES |
| sequence |
X
|
| description |
N6-methyllysine; by KMT5A; alternate => ECO:0000269|PubMed:17707234, ECO:0000269|PubMed:20870725, ECO:0000269|PubMed:22864287
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
6)
|
chain |
A |
| residue |
386 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) => ECO:0000269|PubMed:11124955, ECO:0000269|PubMed:22214662, ECO:0000269|Ref.37
|
| source |
Swiss-Prot : SWS_FT_FI6
|
|
|
|