eF-site ID 1jq7-B PDB Code 1jq7 Chain B click to enlarge Title HCMV protease dimer-interface mutant, S225Y complexed to Inhibitor BILC 408 Classification HYDROLASE/HYDROLASE INHIBITOR Compound ASSEMBLIN Source Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) (VP40_HCMVA) Sequence B:  QSQAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLALP LNINHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVR RASEKSELVSRGPVSPLQPDKVVEFLSGSYAGLSLSSRRC DTTPFKHVALCSVGRRRGTLAVYGRDPEWVTQRFPDLTAA DRDGLRAQWQSGDPFRSDSYGLLGNYVDALYIRERLPKLR YDKQLVGVTERESYVKA Description Functional site 1) chain B residue 1331 type sequence E description BINDING SITE FOR RESIDUE 0FP B 561 source : AC2 2) chain B residue 1362 type sequence N description BINDING SITE FOR RESIDUE 0FP B 561 source : AC2 3) chain B residue 1363 type sequence H description BINDING SITE FOR RESIDUE 0FP B 561 source : AC2 4) chain B residue 1432 type sequence S description BINDING SITE FOR RESIDUE 0FP B 561 source : AC2 5) chain B residue 1433 type sequence L description BINDING SITE FOR RESIDUE 0FP B 561 source : AC2 6) chain B residue 1434 type sequence S description BINDING SITE FOR RESIDUE 0FP B 561 source : AC2 7) chain B residue 1435 type sequence S description BINDING SITE FOR RESIDUE 0FP B 561 source : AC2 8) chain B residue 1436 type sequence R description BINDING SITE FOR RESIDUE 0FP B 561 source : AC2 9) chain B residue 1456 type sequence K description BINDING SITE FOR RESIDUE 0FP B 561 source : AC2 10) chain B residue 1463 type sequence V description BINDING SITE FOR RESIDUE 0FP B 561 source : AC2 11) chain B residue 1464 type sequence G description BINDING SITE FOR RESIDUE 0FP B 561 source : AC2 12) chain B residue 1465 type sequence R description BINDING SITE FOR RESIDUE 0FP B 561 source : AC2 13) chain B residue 1531 type sequence I description BINDING SITE FOR RESIDUE 0FP B 561 source : AC2 14) chain B residue 1363 type catalytic sequence H description 238 source MCSA : MCSA2 15) chain B residue 1432 type catalytic sequence S description 238 source MCSA : MCSA2 16) chain B residue 1434 type catalytic sequence S description 238 source MCSA : MCSA2 17) chain B residue 1457 type catalytic sequence H description 238 source MCSA : MCSA2 18) chain B residue 1465 type catalytic sequence R description 238 source MCSA : MCSA2 19) chain B residue 1466 type catalytic sequence R description 238 source MCSA : MCSA2 20) chain B residue 1363 type ACT_SITE sequence H description Charge relay system => ECO:0000255|HAMAP-Rule:MF_04008 source Swiss-Prot : SWS_FT_FI1 21) chain B residue 1432 type ACT_SITE sequence S description Charge relay system => ECO:0000255|HAMAP-Rule:MF_04008 source Swiss-Prot : SWS_FT_FI1 22) chain B residue 1457 type ACT_SITE sequence H description Charge relay system => ECO:0000255|HAMAP-Rule:MF_04008 source Swiss-Prot : SWS_FT_FI1 23) chain B residue 1556 type SITE sequence A description Cleavage; by assemblin; Release site => ECO:0000255|HAMAP-Rule:MF_04008 source Swiss-Prot : SWS_FT_FI2

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