eF-site ID 1jl2-D
PDB Code 1jl2
Chain D

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Title Crystal structure of TCEO RNase H-a chimera combining the folding core from T. thermophilus RNase H and the remaining region of E. coli RNase H
Classification HYDROLASE
Compound Chimera of Ribonuclease HI, Ribonuclease H
Source Escherichia coli (strain K12) (RNH_ECOLI)
Sequence D:  KQVEIFTDGSALGNPGPGGYGAILRYRGREKTFSAGYTRT
TNNRMELKAAIEGLKALKEPAEVDLYTDSHYLKKAFTEGW
LEGWRTAEGKPVKNRDLWEALLLAMAPHRVRFHFVKGHAG
HPENERADELARAAAMNPTLEDTGYQ
Description


Functional site

1) chain D
residue 10
type catalytic
sequence D
description 163
source MCSA : MCSA4

2) chain D
residue 11
type catalytic
sequence G
description 163
source MCSA : MCSA4

3) chain D
residue 48
type catalytic
sequence E
description 163
source MCSA : MCSA4

4) chain D
residue 125
type catalytic
sequence H
description 163
source MCSA : MCSA4

5) chain D
residue 135
type catalytic
sequence D
description 163
source MCSA : MCSA4

6) chain D
residue 10
type BINDING
sequence D
description BINDING => ECO:0000269|PubMed:1311386
source Swiss-Prot : SWS_FT_FI1

7) chain D
residue 135
type BINDING
sequence D
description BINDING => ECO:0000269|PubMed:1311386
source Swiss-Prot : SWS_FT_FI1

8) chain D
residue 48
type BINDING
sequence E
description BINDING => ECO:0000250
source Swiss-Prot : SWS_FT_FI2

9) chain D
residue 70
type BINDING
sequence D
description BINDING => ECO:0000250
source Swiss-Prot : SWS_FT_FI2


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