|
|
eF-site ID
|
1jl2-A |
|
PDB Code
|
1jl2 |
|
Chain
|
A |
|
click to enlarge
|
|
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Title
|
Crystal structure of TCEO RNase H-a chimera combining the folding core from T. thermophilus RNase H and the remaining region of E. coli RNase H |
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Classification
|
HYDROLASE |
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Compound
|
Chimera of Ribonuclease HI, Ribonuclease H |
|
Source
|
Escherichia coli (strain K12) (RNH_ECOLI) |
|
|
Sequence
|
A: |
KQVEIFTDGSALGNPGPGGYGAILRYRGREKTFSAGYTRT
TNNRMELKAAIEGLKALKEPAEVDLYTDSHYLKKAFTEGW
LEGWRKRGWRTAEGKPVKNRDLWEALLLAMAPHRVRFHFV
KGHAGHPENERADELARAAAMNPTLEDTGY
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
10 |
| type |
catalytic |
| sequence |
D
|
| description |
163
|
| source |
MCSA : MCSA1
|
|
|
2)
|
chain |
A |
| residue |
11 |
| type |
catalytic |
| sequence |
G
|
| description |
163
|
| source |
MCSA : MCSA1
|
|
|
3)
|
chain |
A |
| residue |
48 |
| type |
catalytic |
| sequence |
E
|
| description |
163
|
| source |
MCSA : MCSA1
|
|
|
4)
|
chain |
A |
| residue |
125 |
| type |
catalytic |
| sequence |
H
|
| description |
163
|
| source |
MCSA : MCSA1
|
|
|
5)
|
chain |
A |
| residue |
135 |
| type |
catalytic |
| sequence |
D
|
| description |
163
|
| source |
MCSA : MCSA1
|
|
|
6)
|
chain |
A |
| residue |
48 |
| type |
BINDING |
| sequence |
E
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
7)
|
chain |
A |
| residue |
70 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
8)
|
chain |
A |
| residue |
10 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000269|PubMed:1311386
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
9)
|
chain |
A |
| residue |
135 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000269|PubMed:1311386
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|