eF-site ID 1jg4-A PDB Code 1jg4 Chain A click to enlarge Title Crystal Structure of L-isoaspartyl (D-aspartyl) O-methyltransferase with S-adenosylmethionine Classification TRANSFERASE Compound protein-L-isoaspartate O-methyltransferase Source Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) (PIMT_PYRFU) Sequence A:  EKELYEKWMRTVEMLKAEGIIRSKEVERAFLKYPRYLSVE DKYKKYAHIDEPLPIPAGQTVSAPHMVAIMLEIANLKPGM NILEVGTGSGWNAALISEIVKTDVYTIERIPELVEFAKRN LERAGVKNVHVILGDGSKGFPPKAPYDVIIVTAGAPKIPE PLIEQLKIGGKLIIPVGSYHLWQELLEVRKTKDGIKIKNH GGVAFVPLIGEYGWK Description Functional site 1) chain A residue 72 type sequence Q description BINDING SITE FOR RESIDUE SAM A 500 source : AC1 2) chain A residue 73 type sequence T description BINDING SITE FOR RESIDUE SAM A 500 source : AC1 3) chain A residue 97 type sequence E description BINDING SITE FOR RESIDUE SAM A 500 source : AC1 4) chain A residue 99 type sequence G description BINDING SITE FOR RESIDUE SAM A 500 source : AC1 5) chain A residue 100 type sequence T description BINDING SITE FOR RESIDUE SAM A 500 source : AC1 6) chain A residue 101 type sequence G description BINDING SITE FOR RESIDUE SAM A 500 source : AC1 7) chain A residue 102 type sequence S description BINDING SITE FOR RESIDUE SAM A 500 source : AC1 8) chain A residue 104 type sequence W description BINDING SITE FOR RESIDUE SAM A 500 source : AC1 9) chain A residue 105 type sequence N description BINDING SITE FOR RESIDUE SAM A 500 source : AC1 10) chain A residue 120 type sequence I description BINDING SITE FOR RESIDUE SAM A 500 source : AC1 11) chain A residue 121 type sequence E description BINDING SITE FOR RESIDUE SAM A 500 source : AC1 12) chain A residue 122 type sequence R description BINDING SITE FOR RESIDUE SAM A 500 source : AC1 13) chain A residue 123 type sequence I description BINDING SITE FOR RESIDUE SAM A 500 source : AC1 14) chain A residue 126 type sequence L description BINDING SITE FOR RESIDUE SAM A 500 source : AC1 15) chain A residue 147 type sequence G description BINDING SITE FOR RESIDUE SAM A 500 source : AC1 16) chain A residue 148 type sequence D description BINDING SITE FOR RESIDUE SAM A 500 source : AC1 17) chain A residue 149 type sequence G description BINDING SITE FOR RESIDUE SAM A 500 source : AC1 18) chain A residue 165 type sequence T description BINDING SITE FOR RESIDUE SAM A 500 source : AC1 19) chain A residue 219 type sequence V description BINDING SITE FOR RESIDUE SAM A 500 source : AC1 20) chain A residue 220 type sequence P description BINDING SITE FOR RESIDUE SAM A 500 source : AC1 21) chain A residue 221 type sequence L description BINDING SITE FOR RESIDUE SAM A 500 source : AC1 22) chain A residue 222 type sequence I description BINDING SITE FOR RESIDUE SAM A 500 source : AC1 23) chain A residue 75 type ACT_SITE sequence S description ACT_SITE => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 24) chain A residue 147-162 type prosite sequence GDGSKGFPPKAPYDVI description PCMT Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. GDGskGFppkAPYDvI source prosite : PS01279

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