eF-site ID 1j5j-A
PDB Code 1j5j
Chain A

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Title Solution structure of HERG-specific scorpion toxin BeKm-1
Classification TOXIN
Compound BeKm-1 toxin
Source null (SEKM_BUTEU)
Sequence A:  RPTDIKCSESYQCFPVCKSRFGKTNGRCVNGFCDCF
Description


Functional site

1) chain A
residue 18
type SITE
sequence K
description Crucial for Kv11/ERG channel binding, plugs its side chain into the channel selectivity filter => ECO:0000305|PubMed:12151390, ECO:0000305|PubMed:17269718
source Swiss-Prot : SWS_FT_FI1

2) chain A
residue 20
type SITE
sequence R
description Crucial for Kv11/ERG channel binding => ECO:0000305|PubMed:12151390, ECO:0000305|PubMed:17269718
source Swiss-Prot : SWS_FT_FI2


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