eF-site ID 1j2t-F PDB Code 1j2t Chain F click to enlarge Title Creatininase Mn Classification HYDROLASE Compound creatinine amidohydrolase Source null (P83772_PSEPU) Sequence F:  KSVFVGELTWKEYEARVAAGDCVLMLPVGALEQHGHHMCM NVDVLLPTAVCKRVAERIGALVMPGLQYGYKSQQKSGGGN HFPGTTSLDGATLTGTVQDIIRELARHGARRLVLMNGHYE NSMFIVEGIDLALRELRYAGIQDFKVVVLSYWDFVKDPAV IQQLYPEGFLGWDIEHGGVFETSLMLALYPDLVDLDRVVD HPPATFPPYDVFPVDPARTPAPGTLSSAKTASREKGELIL EVCVQGIADAIREEFPP Description Functional site 1) chain F residue 36 type sequence H description BINDING SITE FOR RESIDUE ZN F 302 source : BC2 2) chain F residue 45 type sequence D description BINDING SITE FOR RESIDUE ZN F 302 source : BC2 3) chain F residue 183 type sequence E description BINDING SITE FOR RESIDUE ZN F 302 source : BC2 4) chain F residue 34 type sequence E description BINDING SITE FOR RESIDUE MN F 301 source : BC3 5) chain F residue 45 type sequence D description BINDING SITE FOR RESIDUE MN F 301 source : BC3 6) chain F residue 120 type sequence H description BINDING SITE FOR RESIDUE MN F 301 source : BC3 7) chain F residue 54 type sequence K description BINDING SITE FOR RESIDUE SO4 F 7004 source : BC7 8) chain F residue 55 type sequence R description BINDING SITE FOR RESIDUE SO4 F 7004 source : BC7 9) chain F residue 191 type sequence Y description BINDING SITE FOR RESIDUE SO4 F 7004 source : BC7 10) chain F residue 113 type sequence R description BINDING SITE FOR RESIDUE SO4 F 7010 source : CC4 11) chain F residue 147 type sequence K description BINDING SITE FOR RESIDUE SO4 F 7010 source : CC4 12) chain F residue 256 type sequence E description BINDING SITE FOR RESIDUE SO4 F 7010 source : CC4 13) chain F residue 257 type sequence F description BINDING SITE FOR RESIDUE SO4 F 7010 source : CC4 14) chain F residue 34 type catalytic sequence E description 720 source MCSA : MCSA6 15) chain F residue 36 type catalytic sequence H description 720 source MCSA : MCSA6 16) chain F residue 45 type catalytic sequence D description 720 source MCSA : MCSA6 17) chain F residue 120 type catalytic sequence H description 720 source MCSA : MCSA6 18) chain F residue 122 type catalytic sequence E description 720 source MCSA : MCSA6 19) chain F residue 178 type catalytic sequence H description 720 source MCSA : MCSA6 20) chain F residue 183 type catalytic sequence E description 720 source MCSA : MCSA6 21) chain F residue 122 type SITE sequence E description Coordinates a catalytic water molecule source Swiss-Prot : SWS_FT_FI4 22) chain F residue 120 type BINDING sequence H description BINDING => ECO:0000269|PubMed:12946365, ECO:0000269|PubMed:20043918, ECO:0007744|PDB:3A6L source Swiss-Prot : SWS_FT_FI1 23) chain F residue 34 type BINDING sequence E description BINDING => ECO:0000269|PubMed:12946365, ECO:0000269|PubMed:20043918, ECO:0007744|PDB:3A6L source Swiss-Prot : SWS_FT_FI1 24) chain F residue 36 type BINDING sequence H description BINDING => ECO:0000269|PubMed:12946365, ECO:0000269|PubMed:15003455, ECO:0000269|PubMed:20043918, ECO:0007744|PDB:1V7Z, ECO:0007744|PDB:3A6J, ECO:0007744|PDB:3A6K, ECO:0007744|PDB:3A6L source Swiss-Prot : SWS_FT_FI2 25) chain F residue 45 type BINDING sequence D description BINDING => ECO:0000269|PubMed:12946365, ECO:0000269|PubMed:15003455, ECO:0000269|PubMed:20043918, ECO:0007744|PDB:1V7Z, ECO:0007744|PDB:3A6J, ECO:0007744|PDB:3A6K, ECO:0007744|PDB:3A6L source Swiss-Prot : SWS_FT_FI2 26) chain F residue 183 type BINDING sequence E description BINDING => ECO:0000269|PubMed:12946365, ECO:0000269|PubMed:15003455, ECO:0000269|PubMed:20043918, ECO:0007744|PDB:1V7Z, ECO:0007744|PDB:3A6J, ECO:0007744|PDB:3A6K, ECO:0007744|PDB:3A6L source Swiss-Prot : SWS_FT_FI2 27) chain F residue 78 type BINDING sequence S description BINDING => ECO:0000269|PubMed:15003455, ECO:0000269|PubMed:20043918, ECO:0007744|PDB:1V7Z, ECO:0007744|PDB:3A6J source Swiss-Prot : SWS_FT_FI3 28) chain F residue 121 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:15003455, ECO:0000269|PubMed:20043918, ECO:0007744|PDB:1V7Z, ECO:0007744|PDB:3A6J source Swiss-Prot : SWS_FT_FI3 29) chain F residue 174 type BINDING sequence W description BINDING => ECO:0000269|PubMed:15003455, ECO:0000269|PubMed:20043918, ECO:0007744|PDB:1V7Z, ECO:0007744|PDB:3A6J source Swiss-Prot : SWS_FT_FI3 30) chain F residue 175 type BINDING sequence D description BINDING => ECO:0000269|PubMed:15003455, ECO:0000269|PubMed:20043918, ECO:0007744|PDB:1V7Z, ECO:0007744|PDB:3A6J source Swiss-Prot : SWS_FT_FI3 31) chain F residue 178 type BINDING sequence H description BINDING => ECO:0000269|PubMed:15003455, ECO:0000269|PubMed:20043918, ECO:0007744|PDB:1V7Z, ECO:0007744|PDB:3A6J source Swiss-Prot : SWS_FT_FI3

Display surface Download Links