eF-site ID 1j2g-A PDB Code 1j2g Chain A click to enlarge Title Crystal structure of Urate oxidase from Bacillus SP. TB-90 co-crystallized with 8-Azaxanthine Classification OXIDOREDUCTASE Compound Uricase Source null (URIC_BACSB) Sequence A:  RVMYYGKGDVFAYRTYLKPLTGVRTIPESPFSGRDHILFG VNVKISVGGTKLLTSFTKGDNSLVVATDSMKNFIQKHLAS YTGTTIEGFLEYVATSFLKKYSHIEKISLIGEEIPFETTF AVKNGNRAASELVFKKSRNEYATAYLNMVRNEDNTLNITE QQSGLAGLQLIKVSGNSFVGFIRDEYTTLPEDSNRPLFVY LNIKWKYKNTEDSFGTNPENYVAAEQIRDIATSVFHETET LSIQHLIYLIGRRILERFPQLQEVYFESQNHTWDKIVEEI PESEGKVYTEPRPPYGFQCFTVTQED Description Functional site 1) chain A residue 106 type sequence K description BINDING SITE FOR RESIDUE SO4 A 502 source : AC2 2) chain A residue 190 type sequence D description BINDING SITE FOR RESIDUE SO4 A 502 source : AC2 3) chain A residue 191 type sequence E description BINDING SITE FOR RESIDUE SO4 A 502 source : AC2 4) chain A residue 31 type sequence T description BINDING SITE FOR RESIDUE SO4 D 503 source : AC3 5) chain A residue 31 type sequence T description BINDING SITE FOR RESIDUE SO4 D 503 source : AC3 6) chain A residue 298 type sequence R description BINDING SITE FOR RESIDUE SO4 A 504 source : AC4 7) chain A residue 184 type sequence F description BINDING SITE FOR RESIDUE AZA A 4320 source : AC5 8) chain A residue 195 type sequence L description BINDING SITE FOR RESIDUE AZA A 4320 source : AC5 9) chain A residue 201 type sequence R description BINDING SITE FOR RESIDUE AZA A 4320 source : AC5 10) chain A residue 248 type sequence S description BINDING SITE FOR RESIDUE AZA A 4320 source : AC5 11) chain A residue 249 type sequence I description BINDING SITE FOR RESIDUE AZA A 4320 source : AC5 12) chain A residue 250 type sequence Q description BINDING SITE FOR RESIDUE AZA A 4320 source : AC5 13) chain A residue 276 type sequence N description BINDING SITE FOR RESIDUE AZA A 4320 source : AC5 14) chain A residue 11 type sequence Y description BINDING SITE FOR RESIDUE AZA B 1320 source : AC6 15) chain A residue 72 type sequence A description BINDING SITE FOR RESIDUE AZA B 1320 source : AC6 16) chain A residue 73 type sequence T description BINDING SITE FOR RESIDUE AZA B 1320 source : AC6 17) chain A residue 73 type BINDING sequence T description BINDING => ECO:0000250|UniProtKB:Q00511 source Swiss-Prot : SWS_FT_FI3 18) chain A residue 74 type BINDING sequence D description BINDING => ECO:0000250|UniProtKB:Q00511 source Swiss-Prot : SWS_FT_FI3 19) chain A residue 249 type BINDING sequence I description BINDING => ECO:0000250|UniProtKB:Q00511 source Swiss-Prot : SWS_FT_FI3 20) chain A residue 250 type BINDING sequence Q description BINDING => ECO:0000250|UniProtKB:Q00511 source Swiss-Prot : SWS_FT_FI3 21) chain A residue 276 type BINDING sequence N description BINDING => ECO:0000250|UniProtKB:Q00511 source Swiss-Prot : SWS_FT_FI3 22) chain A residue 184 type BINDING sequence F description BINDING => ECO:0000305|Ref.3 source Swiss-Prot : SWS_FT_FI4 23) chain A residue 201 type BINDING sequence R description BINDING => ECO:0000305|Ref.3 source Swiss-Prot : SWS_FT_FI4 24) chain A residue 73 type ACT_SITE sequence T description Charge relay system; for urate oxidase activity => ECO:0000250|UniProtKB:D0VWQ1 source Swiss-Prot : SWS_FT_FI1 25) chain A residue 13 type ACT_SITE sequence K description Charge relay system; for urate oxidase activity => ECO:0000250|UniProtKB:D0VWQ1 source Swiss-Prot : SWS_FT_FI1 26) chain A residue 174-201 type prosite sequence LQLIKVSGNSFVGFIRDEYTTLPEDSNR description URICASE Uricase signature. LqLIKVSgNsFvgFirdeYttLpedsnR source prosite : PS00366 27) chain A residue 24 type ACT_SITE sequence K description Charge relay system => ECO:0000250|UniProtKB:Q00511 source Swiss-Prot : SWS_FT_FI2

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