eF-site ID 1j1c-B PDB Code 1j1c Chain B click to enlarge Title Binary complex structure of human tau protein kinase I with ADP Classification TRANSFERASE Compound Glycogen synthase kinase-3 beta Source Homo sapiens (Human) (GSK3B_HUMAN) Sequence B:  FGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVI GNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMR KLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRV ARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDI KPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYY RAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSG VDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWT KVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDE LRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHA RIQA Description Functional site 1) chain B residue 686 type sequence N description BINDING SITE FOR RESIDUE MG B 931 source : AC2 2) chain B residue 700 type sequence D description BINDING SITE FOR RESIDUE MG B 931 source : AC2 3) chain B residue 562 type sequence I description BINDING SITE FOR RESIDUE ADP B 930 source : AC4 4) chain B residue 565 type sequence G description BINDING SITE FOR RESIDUE ADP B 930 source : AC4 5) chain B residue 570 type sequence V description BINDING SITE FOR RESIDUE ADP B 930 source : AC4 6) chain B residue 583 type sequence A description BINDING SITE FOR RESIDUE ADP B 930 source : AC4 7) chain B residue 585 type sequence K description BINDING SITE FOR RESIDUE ADP B 930 source : AC4 8) chain B residue 610 type sequence V description BINDING SITE FOR RESIDUE ADP B 930 source : AC4 9) chain B residue 633 type sequence D description BINDING SITE FOR RESIDUE ADP B 930 source : AC4 10) chain B residue 634 type sequence Y description BINDING SITE FOR RESIDUE ADP B 930 source : AC4 11) chain B residue 635 type sequence V description BINDING SITE FOR RESIDUE ADP B 930 source : AC4 12) chain B residue 638 type sequence T description BINDING SITE FOR RESIDUE ADP B 930 source : AC4 13) chain B residue 685 type sequence Q description BINDING SITE FOR RESIDUE ADP B 930 source : AC4 14) chain B residue 686 type sequence N description BINDING SITE FOR RESIDUE ADP B 930 source : AC4 15) chain B residue 688 type sequence L description BINDING SITE FOR RESIDUE ADP B 930 source : AC4 16) chain B residue 700 type sequence D description BINDING SITE FOR RESIDUE ADP B 930 source : AC4 17) chain B residue 681 type ACT_SITE sequence D description Proton acceptor source Swiss-Prot : SWS_FT_FI1 18) chain B residue 562 type BINDING sequence I description BINDING => ECO:0000255|PROSITE-ProRule:PRU00159 source Swiss-Prot : SWS_FT_FI2 19) chain B residue 585 type BINDING sequence K description BINDING => ECO:0000255|PROSITE-ProRule:PRU00159, ECO:0000305|PubMed:17050006 source Swiss-Prot : SWS_FT_FI3 20) chain B residue 716 type MOD_RES sequence Y description Phosphotyrosine => ECO:0000269|PubMed:12554650, ECO:0000269|PubMed:25169422 source Swiss-Prot : SWS_FT_FI5

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