|
|
eF-site ID
|
1ikf-L |
|
PDB Code
|
1ikf |
|
Chain
|
L |
|
click to enlarge
|
|
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Title
|
A CONFORMATION OF CYCLOSPORIN A IN AQUEOUS ENVIRONMENT REVEALED BY THE X-RAY STRUCTURE OF A CYCLOSPORIN-FAB COMPLEX |
|
Classification
|
IMMUNE SYSTEM/IMMUNOSUPPRESSANT |
|
Compound
|
IGG1-KAPPA R45-45-11 FAB (LIGHT CHAIN) |
|
Source
|
(NOR00033) |
|
|
Sequence
|
L: |
DIQMTQTTSSLSASLGDRVTISCRASQDISTYLNWYQQKP
DGTVKLLIFYTSRLRSGVPSRFSGSGSGTDYSLTISNLEQ
EDIATYFCQQGSRIPPTFGGGTKLEILRADAAPTVSIFPP
SSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL
NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKT
STSPIVKSFNRAAC
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
L |
| residue |
50 |
| type |
|
| sequence |
Y
|
| description |
BINDING SITE FOR CHAIN C OF CYCLOSPORIN A
|
| source |
: AC1
|
|
|
2)
|
chain |
L |
| residue |
91 |
| type |
|
| sequence |
G
|
| description |
BINDING SITE FOR CHAIN C OF CYCLOSPORIN A
|
| source |
: AC1
|
|
|
3)
|
chain |
L |
| residue |
92 |
| type |
|
| sequence |
S
|
| description |
BINDING SITE FOR CHAIN C OF CYCLOSPORIN A
|
| source |
: AC1
|
|
|
4)
|
chain |
L |
| residue |
94 |
| type |
|
| sequence |
I
|
| description |
BINDING SITE FOR CHAIN C OF CYCLOSPORIN A
|
| source |
: AC1
|
|
|
5)
|
chain |
L |
| residue |
192-198 |
| type |
prosite |
| sequence |
YTCEATH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH
|
| source |
prosite : PS00290
|
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|
|