|
|
eF-site ID
|
1ik9-ABC |
|
PDB Code
|
1ik9 |
|
Chain
|
A, B, C |
|
|
|
|
Title
|
CRYSTAL STRUCTURE OF A XRCC4-DNA LIGASE IV COMPLEX |
|
Classification
|
GENE REGULATION/LIGASE |
|
Compound
|
DNA REPAIR PROTEIN XRCC4 |
|
Source
|
Homo sapiens (Human) (DNL4_HUMAN) |
|
|
Sequence
|
A: |
MERKISRIHLVSEPSITHFLQVSWEKTLESGFVITLTDGH
SAWTGTVSESEISQEADDMAMEKGKYVGELRKALLSADVY
TFNFSKESAYFFFEKNLKDVSFRLGSFNLEKVENPAEVIR
ELIAYALDTIAENQAKNEHLQKENERLLRDWNDVQGRFEK
AVSAKEALETDLYKRFILVLNEKKTKIRSLHNKLLNAAQE
REKDIKQ
|
| B: |
MERKISRIHLVSEPSITHFLQVSWEKTLESGFVITLTDGH
SAWTGTVSESEISQEADDMAMEKGKYVGELRKALLSVYTF
NFSKESAYFFFEKNLKDVSFRLGSFNLEKVENPAEVIREL
IAYALDTIAENQAKNEHLQKENERLLRDWNDVQGRFEKAV
SAKEALETDLYKRFILVLNEKKTKIRSLHNKLLNA
|
| C: |
AREYDCYGDSYFIDTDLNQLKEVFSGIK
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
53 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by PRKDC => ECO:0000269|PubMed:14599745
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
B |
| residue |
53 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by PRKDC => ECO:0000269|PubMed:14599745
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
A |
| residue |
193 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by PRKDC => ECO:0000269|PubMed:14599745, ECO:0000269|PubMed:22228831, ECO:0000269|PubMed:28500754
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
B |
| residue |
193 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by PRKDC => ECO:0000269|PubMed:14599745, ECO:0000269|PubMed:22228831, ECO:0000269|PubMed:28500754
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
A |
| residue |
210 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) => ECO:0000269|PubMed:16478998
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|