eF-site ID 1ih8-A
PDB Code 1ih8
Chain A

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Title NH3-dependent NAD+ Synthetase from Bacillus subtilis Complexed with AMP-CPP and Mg2+ ions.
Classification LIGASE
Compound NH(3)-DEPENDENT NAD(+) synthetase
Source null (NADE_BACSU)
Sequence A:  SMQEKIMRELHVKPSIDPKQEIEDRVNFLKQYVKKTGAKG
FVLGISGGQDSTLAGRLAQLAVESIREEGGDAQFIAVRLP
HGTQQDEDDAQLALKFIKPDKSWKFDIKSTVSAFSDQYQQ
ETGDQLTDFNKGNVKARTRMIAQYAIGGQEGLLVLGTDHA
AEAVTGFFTKYGDGGADLLPLTGLTKRQGRTLLKELGAPE
RLYLKEPTADLLDEKPQQSDETELGISYDEIDDYLEGKEV
SAKVSEALEKRYSMTEHKRQVPASMFDDWWK
Description


Functional site
1) chain A
residue 208
type
sequence T
description BINDING SITE FOR RESIDUE MG A 4002
source : AC1
2) chain A
residue 162
type
sequence E
description BINDING SITE FOR RESIDUE MG A 4003
source : AC2
3) chain A
residue 43
type
sequence L
description BINDING SITE FOR RESIDUE APC A 3001
source : AC4
4) chain A
residue 44
type
sequence G
description BINDING SITE FOR RESIDUE APC A 3001
source : AC4
5) chain A
residue 45
type
sequence I
description BINDING SITE FOR RESIDUE APC A 3001
source : AC4
6) chain A
residue 46
type
sequence S
description BINDING SITE FOR RESIDUE APC A 3001
source : AC4
7) chain A
residue 48
type
sequence G
description BINDING SITE FOR RESIDUE APC A 3001
source : AC4
8) chain A
residue 49
type
sequence Q
description BINDING SITE FOR RESIDUE APC A 3001
source : AC4
9) chain A
residue 50
type
sequence D
description BINDING SITE FOR RESIDUE APC A 3001
source : AC4
10) chain A
residue 51
type
sequence S
description BINDING SITE FOR RESIDUE APC A 3001
source : AC4
11) chain A
residue 78
type
sequence R
description BINDING SITE FOR RESIDUE APC A 3001
source : AC4
12) chain A
residue 79
type
sequence L
description BINDING SITE FOR RESIDUE APC A 3001
source : AC4
13) chain A
residue 84
type
sequence Q
description BINDING SITE FOR RESIDUE APC A 3001
source : AC4
14) chain A
residue 139
type
sequence R
description BINDING SITE FOR RESIDUE APC A 3001
source : AC4
15) chain A
residue 157
type
sequence T
description BINDING SITE FOR RESIDUE APC A 3001
source : AC4
16) chain A
residue 186
type
sequence K
description BINDING SITE FOR RESIDUE APC A 3001
source : AC4
17) chain A
residue 207
type
sequence P
description BINDING SITE FOR RESIDUE APC A 3001
source : AC4
18) chain A
residue 208
type
sequence T
description BINDING SITE FOR RESIDUE APC A 3001
source : AC4
19) chain A
residue 209
type
sequence A
description BINDING SITE FOR RESIDUE APC A 3001
source : AC4
20) chain A
residue 224
type BINDING
sequence L
description in other chain => ECO:0007744|PDB:1EE1, ECO:0007744|PDB:1KQP, ECO:0007744|PDB:2NSY
source Swiss-Prot : SWS_FT_FI9
21) chain A
residue 51
type catalytic
sequence S
description 200
source MCSA : MCSA1
22) chain A
residue 163
type catalytic
sequence A
description 200
source MCSA : MCSA1
23) chain A
residue 33
type BINDING
sequence V
description BINDING => ECO:0007744|PDB:1EE1, ECO:0007744|PDB:1IFX, ECO:0007744|PDB:1KQP, ECO:0007744|PDB:2NSY
source Swiss-Prot : SWS_FT_FI1
24) chain A
residue 45
type BINDING
sequence I
description BINDING => ECO:0000255|HAMAP-Rule:MF_00193, ECO:0007744|PDB:1EE1, ECO:0007744|PDB:1FYD, ECO:0007744|PDB:1IH8, ECO:0007744|PDB:1KQP, ECO:0007744|PDB:1NSY, ECO:0007744|PDB:2NSY
source Swiss-Prot : SWS_FT_FI2
25) chain A
residue 187
type BINDING
sequence R
description BINDING => ECO:0000255|HAMAP-Rule:MF_00193, ECO:0007744|PDB:1EE1, ECO:0007744|PDB:1FYD, ECO:0007744|PDB:1IH8, ECO:0007744|PDB:1KQP, ECO:0007744|PDB:1NSY, ECO:0007744|PDB:2NSY
source Swiss-Prot : SWS_FT_FI2
26) chain A
residue 51
type BINDING
sequence S
description BINDING => ECO:0000255|HAMAP-Rule:MF_00193, ECO:0007744|PDB:1KQP, ECO:0007744|PDB:1NSY, ECO:0007744|PDB:2NSY
source Swiss-Prot : SWS_FT_FI3
27) chain A
residue 163
type BINDING
sequence A
description BINDING => ECO:0000255|HAMAP-Rule:MF_00193, ECO:0007744|PDB:1KQP, ECO:0007744|PDB:1NSY, ECO:0007744|PDB:2NSY
source Swiss-Prot : SWS_FT_FI3
28) chain A
residue 79
type BINDING
sequence L
description BINDING => ECO:0007744|PDB:1EE1, ECO:0007744|PDB:1FYD, ECO:0007744|PDB:1IH8, ECO:0007744|PDB:1KQP, ECO:0007744|PDB:1NSY, ECO:0007744|PDB:2NSY
source Swiss-Prot : SWS_FT_FI4
29) chain A
residue 85
type BINDING
sequence Q
description BINDING => ECO:0007744|PDB:1EE1, ECO:0007744|PDB:1FYD, ECO:0007744|PDB:1IH8, ECO:0007744|PDB:1KQP, ECO:0007744|PDB:1NSY, ECO:0007744|PDB:2NSY
source Swiss-Prot : SWS_FT_FI4
30) chain A
residue 138
type BINDING
sequence T
description in other chain => ECO:0000255|HAMAP-Rule:MF_00193, ECO:0007744|PDB:1EE1, ECO:0007744|PDB:1IFX, ECO:0007744|PDB:1KQP, ECO:0007744|PDB:2NSY
source Swiss-Prot : SWS_FT_FI5
31) chain A
residue 171
type BINDING
sequence Y
description in other chain => ECO:0000255|HAMAP-Rule:MF_00193, ECO:0007744|PDB:1EE1, ECO:0007744|PDB:1IFX, ECO:0007744|PDB:1KQP, ECO:0007744|PDB:2NSY
source Swiss-Prot : SWS_FT_FI5
32) chain A
residue 258
type BINDING
sequence K
description in other chain => ECO:0000255|HAMAP-Rule:MF_00193, ECO:0007744|PDB:1EE1, ECO:0007744|PDB:1IFX, ECO:0007744|PDB:1KQP, ECO:0007744|PDB:2NSY
source Swiss-Prot : SWS_FT_FI5
33) chain A
residue 158
type BINDING
sequence D
description BINDING => ECO:0000255|HAMAP-Rule:MF_00193, ECO:0007744|PDB:1EE1, ECO:0007744|PDB:1KQP, ECO:0007744|PDB:1NSY, ECO:0007744|PDB:2NSY
source Swiss-Prot : SWS_FT_FI6
34) chain A
residue 178
type BINDING
sequence L
description BINDING => ECO:0000255|HAMAP-Rule:MF_00193, ECO:0007744|PDB:1EE1, ECO:0007744|PDB:1IFX, ECO:0007744|PDB:1KQP, ECO:0007744|PDB:2NSY
source Swiss-Prot : SWS_FT_FI7
35) chain A
residue 209
type BINDING
sequence A
description BINDING => ECO:0000255|HAMAP-Rule:MF_00193, ECO:0007744|PDB:1EE1, ECO:0007744|PDB:1FYD, ECO:0007744|PDB:1IH8, ECO:0007744|PDB:1NSY, ECO:0007744|PDB:2NSY
source Swiss-Prot : SWS_FT_FI8

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