eF-site ID 1ie6_5-A
PDB Code 1ie6
Model 5
Chain A

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Title SOLUTION STRUCTURE OF IMPERATOXIN A
Classification TOXIN
Compound IMPERATOXIN A
Source null (IPTXA_PANIM)
Sequence A:  GDCLPHLKRCKADNDCCGKKCKRRGTNAEKRCR
Description


Functional site

1) chain A
residue 6
type SITE
sequence H
description Important for stimulation of [3H]ryanodine binding to RYR1 => ECO:0000269|PubMed:14535845
source Swiss-Prot : SWS_FT_FI1

2) chain A
residue 11
type SITE
sequence K
description Important for stimulation of [3H]ryanodine binding to RYR1 => ECO:0000269|PubMed:14535845
source Swiss-Prot : SWS_FT_FI1

3) chain A
residue 30
type SITE
sequence K
description Important for stimulation of [3H]ryanodine binding to RYR1 => ECO:0000269|PubMed:14535845
source Swiss-Prot : SWS_FT_FI1

4) chain A
residue 7
type SITE
sequence L
description Essential for stimulation of [3H]ryanodine binding to RYR1 => ECO:0000269|PubMed:14535845
source Swiss-Prot : SWS_FT_FI2

5) chain A
residue 31
type SITE
sequence R
description Essential for stimulation of [3H]ryanodine binding to RYR1 => ECO:0000269|PubMed:14535845
source Swiss-Prot : SWS_FT_FI2

6) chain A
residue 33
type SITE
sequence R
description Essential for stimulation of [3H]ryanodine binding to RYR1 => ECO:0000269|PubMed:14535845
source Swiss-Prot : SWS_FT_FI2

7) chain A
residue 3-32
type prosite
sequence CLPHLKRCKADNDCCGKKCKRRGTNAEKRC
description SCORPION_CALCINE Scorpion calcine family signature. ClphlkrCkadndCCgkkCkrrgtnaekRC
source prosite : PS60028


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