eF-site ID 1i7i-B PDB Code 1i7i Chain B click to enlarge Title CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF HUMAN PPAR-GAMMA IN COMPLEX WITH THE AGONIST AZ 242 Classification TRANSCRIPTION Compound PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA Source Homo sapiens (Human) (PPAT_HUMAN) Sequence B:  ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSP FVIYDMNSLMMGEDKIKFKHIKEVAIRIFQGCQFRSVEAV QEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASL MNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVK FNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNL LQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLL QVIKKTETSLHPLLQEIY Description Functional site 1) chain B residue 264 type sequence F description BINDING SITE FOR RESIDUE AZ2 B 478 source : AC2 2) chain B residue 266 type sequence H description BINDING SITE FOR RESIDUE AZ2 B 478 source : AC2 3) chain B residue 281 type sequence I description BINDING SITE FOR RESIDUE AZ2 B 478 source : AC2 4) chain B residue 282 type sequence F description BINDING SITE FOR RESIDUE AZ2 B 478 source : AC2 5) chain B residue 284 type sequence G description BINDING SITE FOR RESIDUE AZ2 B 478 source : AC2 6) chain B residue 285 type sequence C description BINDING SITE FOR RESIDUE AZ2 B 478 source : AC2 7) chain B residue 289 type sequence S description BINDING SITE FOR RESIDUE AZ2 B 478 source : AC2 8) chain B residue 323 type sequence H description BINDING SITE FOR RESIDUE AZ2 B 478 source : AC2 9) chain B residue 341 type sequence I description BINDING SITE FOR RESIDUE AZ2 B 478 source : AC2 10) chain B residue 348 type sequence M description BINDING SITE FOR RESIDUE AZ2 B 478 source : AC2 11) chain B residue 364 type sequence M description BINDING SITE FOR RESIDUE AZ2 B 478 source : AC2 12) chain B residue 449 type sequence H description BINDING SITE FOR RESIDUE AZ2 B 478 source : AC2 13) chain B residue 286 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 14) chain B residue 323 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 15) chain B residue 449 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 16) chain B residue 473 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 17) chain B residue 224 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2

Display surface Download Links