eF-site ID 1i38-A PDB Code 1i38 Chain A click to enlarge Title CRYSTAL STRUCTURE OF THE RAT ANDROGEN RECEPTOR LIGAND BINDING DOMAIN T877A MUTANT COMPLEX WITH DIHYDROTESTOSTERONE Classification HORMONE/GROWTH FACTOR Compound ANDROGEN RECEPTOR Source Rattus norvegicus (Rat) (ANDR_RAT) Sequence A:  IFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQ LVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGW RSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLS QEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELR MNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIAR ELHQFAFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKV KPIYFHT Description Functional site 1) chain A residue 704 type sequence L description BINDING SITE FOR RESIDUE DHT A 201 source : AC1 2) chain A residue 705 type sequence N description BINDING SITE FOR RESIDUE DHT A 201 source : AC1 3) chain A residue 711 type sequence Q description BINDING SITE FOR RESIDUE DHT A 201 source : AC1 4) chain A residue 742 type sequence M description BINDING SITE FOR RESIDUE DHT A 201 source : AC1 5) chain A residue 745 type sequence M description BINDING SITE FOR RESIDUE DHT A 201 source : AC1 6) chain A residue 752 type sequence R description BINDING SITE FOR RESIDUE DHT A 201 source : AC1 7) chain A residue 764 type sequence F description BINDING SITE FOR RESIDUE DHT A 201 source : AC1 8) chain A residue 877 type sequence A description BINDING SITE FOR RESIDUE DHT A 201 source : AC1 9) chain A residue 891 type sequence F description BINDING SITE FOR RESIDUE DHT A 201 source : AC1 10) chain A residue 895 type sequence M description BINDING SITE FOR RESIDUE DHT A 201 source : AC1 11) chain A residue 705 type BINDING sequence N description BINDING => ECO:0000269|PubMed:11320241, ECO:0007744|PDB:1I37 source Swiss-Prot : SWS_FT_FI1 12) chain A residue 752 type BINDING sequence R description BINDING => ECO:0000269|PubMed:11320241, ECO:0007744|PDB:1I37 source Swiss-Prot : SWS_FT_FI1 13) chain A residue 877 type BINDING sequence A description BINDING => ECO:0000269|PubMed:11320241, ECO:0007744|PDB:1I37 source Swiss-Prot : SWS_FT_FI1 14) chain A residue 720 type SITE sequence K description Interaction with coactivator LXXL and FXXFY motifs => ECO:0000250|UniProtKB:P10275 source Swiss-Prot : SWS_FT_FI2 15) chain A residue 897 type SITE sequence E description Interaction with coactivator FXXLF and FXXFY motifs => ECO:0000250|UniProtKB:P10275 source Swiss-Prot : SWS_FT_FI3 16) chain A residue 915 type MOD_RES sequence Y description Phosphotyrosine; by CSK => ECO:0000250|UniProtKB:P10275 source Swiss-Prot : SWS_FT_FI4 17) chain A residue 845 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P10275 source Swiss-Prot : SWS_FT_FI5 18) chain A residue 847 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P10275 source Swiss-Prot : SWS_FT_FI5

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