eF-site ID 1i32-E PDB Code 1i32 Chain E click to enlarge Title LEISHMANIA MEXICANA GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE IN COMPLEX WITH INHIBITORS Classification OXIDOREDUCTASE Compound GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE Source Leishmania mexicana (G3PG_LEIME) Sequence E:  APIKVGINGFGRIGRMVFQAICDQGLIGTEIDVVAVVDMS TNAEYFAYQMKHDTVHGRPKYTVEAVKSSPSVETADVLVV NGHRIKCVKAQRNPADLPWGKLGVDYVIESTGLFTDKLKA EGHIKGGAKKVVISAPASGGAKTIVMGVNQHEYSPASHHV VSNASCTTNCLAPIVHVLTKENFGIETGLMTTIHSYTATQ KTVDGVSLKDWRGGRAAAVNIIPSTTGAAKAVGMVIPSTK GKLTGMSFRVPTPDVSVVDLTFRATRDTSIQEIDKAIKKA AQTYMKGILGFTDEELVSADFINDNRSSVYDSKATLQNNL PGEKRFFKVVSWYDNEWAYSHRVVDLVRYMAAKDAASS Description Functional site 1) chain E residue 8 type sequence N description BINDING SITE FOR RESIDUE NMD E 365 source : AC5 2) chain E residue 9 type sequence G description BINDING SITE FOR RESIDUE NMD E 365 source : AC5 3) chain E residue 11 type sequence G description BINDING SITE FOR RESIDUE NMD E 365 source : AC5 4) chain E residue 38 type sequence D description BINDING SITE FOR RESIDUE NMD E 365 source : AC5 5) chain E residue 39 type sequence M description BINDING SITE FOR RESIDUE NMD E 365 source : AC5 6) chain E residue 40 type sequence S description BINDING SITE FOR RESIDUE NMD E 365 source : AC5 7) chain E residue 90 type sequence A description BINDING SITE FOR RESIDUE NMD E 365 source : AC5 8) chain E residue 91 type sequence Q description BINDING SITE FOR RESIDUE NMD E 365 source : AC5 9) chain E residue 92 type sequence R description BINDING SITE FOR RESIDUE NMD E 365 source : AC5 10) chain E residue 111 type sequence T description BINDING SITE FOR RESIDUE NMD E 365 source : AC5 11) chain E residue 113 type sequence L description BINDING SITE FOR RESIDUE NMD E 365 source : AC5 12) chain E residue 206 type sequence V description BINDING SITE FOR RESIDUE NMD F 366 source : AC6 13) chain E residue 166 type BINDING sequence C description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 14) chain E residue 198 type BINDING sequence A description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 15) chain E residue 227 type BINDING sequence G description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 16) chain E residue 250 type BINDING sequence V description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 17) chain E residue 195 type SITE sequence S description Activates thiol group during catalysis source Swiss-Prot : SWS_FT_FI4 18) chain E residue 167 type ACT_SITE sequence T description Nucleophile source Swiss-Prot : SWS_FT_FI1 19) chain E residue 13 type BINDING sequence I description BINDING => ECO:0000269|PubMed:7578111, ECO:0000269|PubMed:9571030 source Swiss-Prot : SWS_FT_FI2 20) chain E residue 39 type BINDING sequence M description BINDING => ECO:0000269|PubMed:7578111, ECO:0000269|PubMed:9571030 source Swiss-Prot : SWS_FT_FI2 21) chain E residue 92 type BINDING sequence R description BINDING => ECO:0000269|PubMed:7578111, ECO:0000269|PubMed:9571030 source Swiss-Prot : SWS_FT_FI2 22) chain E residue 135 type BINDING sequence A description BINDING => ECO:0000269|PubMed:7578111, ECO:0000269|PubMed:9571030 source Swiss-Prot : SWS_FT_FI2 23) chain E residue 336 type BINDING sequence E description BINDING => ECO:0000269|PubMed:7578111, ECO:0000269|PubMed:9571030 source Swiss-Prot : SWS_FT_FI2

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