eF-site ID 1i32-B PDB Code 1i32 Chain B click to enlarge Title LEISHMANIA MEXICANA GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE IN COMPLEX WITH INHIBITORS Classification OXIDOREDUCTASE Compound GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE Source Leishmania mexicana (G3PG_LEIME) Sequence B:  APIKVGINGFGRIGRMVFQAICDQGLIGTEIDVVAVVDMS TNAEYFAYQMKHDTVHGRPKYTVEAVKSSPSVETADVLVV NGHRIKCVKAQRNPADLPWGKLGVDYVIESTGLFTDKLKA EGHIKGGAKKVVISAPASGGAKTIVMGVNQHEYSPASHHV VSNASCTTNCLAPIVHVLTKENFGIETGLMTTIHSYTATQ KTVDGVSLKDWRGGRAAAVNIIPSTTGAAKAVGMVIPSTK GKLTGMSFRVPTPDVSVVDLTFRATRDTSIQEIDKAIKKA AQTYMKGILGFTDEELVSADFINDNRSSVYDSKATLQNNL PGEKRFFKVVSWYDNEWAYSHRVVDLVRYMAAKDAASS Description Functional site 1) chain B residue 206 type sequence V description BINDING SITE FOR RESIDUE NMD A 361 source : AC1 2) chain B residue 8 type sequence N description BINDING SITE FOR RESIDUE NMD B 362 source : AC2 3) chain B residue 9 type sequence G description BINDING SITE FOR RESIDUE NMD B 362 source : AC2 4) chain B residue 11 type sequence G description BINDING SITE FOR RESIDUE NMD B 362 source : AC2 5) chain B residue 37 type sequence V description BINDING SITE FOR RESIDUE NMD B 362 source : AC2 6) chain B residue 38 type sequence D description BINDING SITE FOR RESIDUE NMD B 362 source : AC2 7) chain B residue 39 type sequence M description BINDING SITE FOR RESIDUE NMD B 362 source : AC2 8) chain B residue 40 type sequence S description BINDING SITE FOR RESIDUE NMD B 362 source : AC2 9) chain B residue 90 type sequence A description BINDING SITE FOR RESIDUE NMD B 362 source : AC2 10) chain B residue 91 type sequence Q description BINDING SITE FOR RESIDUE NMD B 362 source : AC2 11) chain B residue 92 type sequence R description BINDING SITE FOR RESIDUE NMD B 362 source : AC2 12) chain B residue 111 type sequence T description BINDING SITE FOR RESIDUE NMD B 362 source : AC2 13) chain B residue 113 type sequence L description BINDING SITE FOR RESIDUE NMD B 362 source : AC2 14) chain B residue 166 type BINDING sequence C description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 15) chain B residue 198 type BINDING sequence A description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 16) chain B residue 227 type BINDING sequence G description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 17) chain B residue 250 type BINDING sequence V description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 18) chain B residue 195 type SITE sequence S description Activates thiol group during catalysis source Swiss-Prot : SWS_FT_FI4 19) chain B residue 167 type ACT_SITE sequence T description Nucleophile source Swiss-Prot : SWS_FT_FI1 20) chain B residue 336 type BINDING sequence E description BINDING => ECO:0000269|PubMed:7578111, ECO:0000269|PubMed:9571030 source Swiss-Prot : SWS_FT_FI2 21) chain B residue 13 type BINDING sequence I description BINDING => ECO:0000269|PubMed:7578111, ECO:0000269|PubMed:9571030 source Swiss-Prot : SWS_FT_FI2 22) chain B residue 39 type BINDING sequence M description BINDING => ECO:0000269|PubMed:7578111, ECO:0000269|PubMed:9571030 source Swiss-Prot : SWS_FT_FI2 23) chain B residue 92 type BINDING sequence R description BINDING => ECO:0000269|PubMed:7578111, ECO:0000269|PubMed:9571030 source Swiss-Prot : SWS_FT_FI2 24) chain B residue 135 type BINDING sequence A description BINDING => ECO:0000269|PubMed:7578111, ECO:0000269|PubMed:9571030 source Swiss-Prot : SWS_FT_FI2

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