eF-site ID 1i32-A PDB Code 1i32 Chain A click to enlarge Title LEISHMANIA MEXICANA GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE IN COMPLEX WITH INHIBITORS Classification OXIDOREDUCTASE Compound GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE Source null (G3PG_LEIME) Sequence A:  APIKVGINGFGRIGRMVFQAICDQGLIGTEIDVVAVVDMS TNAEYFAYQMKHDTVHGRPKYTVEAVKSSPSVETADVLVV NGHRIKCVKAQRNPADLPWGKLGVDYVIESTGLFTDKLKA EGHIKGGAKKVVISAPASGGAKTIVMGVNQHEYSPASHHV VSNASCTTNCLAPIVHVLTKENFGIETGLMTTIHSYTATQ KTVDGVSLKDWRGGRAAAVNIIPSTTGAAKAVGMVIPSTK GKLTGMSFRVPTPDVSVVDLTFRATRDTSIQEIDKAIKKA AQTYMKGILGFTDEELVSADFINDNRSSVYDSKATLQNNL PGEKRFFKVVSWYDNEWAYSHRVVDLVRYMAAKDAASS Description Functional site 1) chain A residue 8 type sequence N description BINDING SITE FOR RESIDUE NMD A 361 source : AC1 2) chain A residue 9 type sequence G description BINDING SITE FOR RESIDUE NMD A 361 source : AC1 3) chain A residue 11 type sequence G description BINDING SITE FOR RESIDUE NMD A 361 source : AC1 4) chain A residue 37 type sequence V description BINDING SITE FOR RESIDUE NMD A 361 source : AC1 5) chain A residue 38 type sequence D description BINDING SITE FOR RESIDUE NMD A 361 source : AC1 6) chain A residue 39 type sequence M description BINDING SITE FOR RESIDUE NMD A 361 source : AC1 7) chain A residue 40 type sequence S description BINDING SITE FOR RESIDUE NMD A 361 source : AC1 8) chain A residue 90 type sequence A description BINDING SITE FOR RESIDUE NMD A 361 source : AC1 9) chain A residue 91 type sequence Q description BINDING SITE FOR RESIDUE NMD A 361 source : AC1 10) chain A residue 92 type sequence R description BINDING SITE FOR RESIDUE NMD A 361 source : AC1 11) chain A residue 111 type sequence T description BINDING SITE FOR RESIDUE NMD A 361 source : AC1 12) chain A residue 113 type sequence L description BINDING SITE FOR RESIDUE NMD A 361 source : AC1 13) chain A residue 206 type sequence V description BINDING SITE FOR RESIDUE NMD B 362 source : AC2 14) chain A residue 167 type ACT_SITE sequence T description Nucleophile source Swiss-Prot : SWS_FT_FI1 15) chain A residue 166 type BINDING sequence C description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 16) chain A residue 198 type BINDING sequence A description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 17) chain A residue 227 type BINDING sequence G description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 18) chain A residue 250 type BINDING sequence V description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 19) chain A residue 195 type SITE sequence S description Activates thiol group during catalysis source Swiss-Prot : SWS_FT_FI4 20) chain A residue 164-171 type prosite sequence ASCTTNCL description GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. ASCTTNcL source prosite : PS00071 21) chain A residue 13 type BINDING sequence I description BINDING => ECO:0000269|PubMed:7578111, ECO:0000269|PubMed:9571030 source Swiss-Prot : SWS_FT_FI2 22) chain A residue 39 type BINDING sequence M description BINDING => ECO:0000269|PubMed:7578111, ECO:0000269|PubMed:9571030 source Swiss-Prot : SWS_FT_FI2 23) chain A residue 92 type BINDING sequence R description BINDING => ECO:0000269|PubMed:7578111, ECO:0000269|PubMed:9571030 source Swiss-Prot : SWS_FT_FI2 24) chain A residue 135 type BINDING sequence A description BINDING => ECO:0000269|PubMed:7578111, ECO:0000269|PubMed:9571030 source Swiss-Prot : SWS_FT_FI2 25) chain A residue 336 type BINDING sequence E description BINDING => ECO:0000269|PubMed:7578111, ECO:0000269|PubMed:9571030 source Swiss-Prot : SWS_FT_FI2

Display surface Download Links