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|
eF-site ID
|
1i31-AP |
|
PDB Code
|
1i31 |
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Chain
|
A, P |
|
click to enlarge
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Title
|
MU2 ADAPTIN SUBUNIT (AP50) OF AP2 CLATHRIN ADAPTOR, COMPLEXED WITH EGFR INTERNALIZATION PEPTIDE FYRALM AT 2.5 A RESOLUTION |
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Classification
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ENDOCYTOSIS/EXOCYTOSIS |
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Compound
|
CLATHRIN COAT ASSEMBLY PROTEIN AP50 |
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Source
|
Rattus norvegicus (Rat) (AAF14008) |
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Sequence
|
A: |
IGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSG
RVVMKSYLSGMPECKFGMNDKIKQSIAIDDCTFHQCVRLS
ERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRT
KLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMK
GKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKK
KWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVI
KWVRYIGRSGIYETRC
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| P: |
FYRALM
|
|
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Description
|
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Functional site
|
|
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1)
|
chain |
A |
| residue |
159-179 |
| type |
prosite |
| sequence |
IGWRREGIKYRRNELFLDVLE
|
| description |
CLAT_ADAPTOR_M_1 Clathrin adaptor complexes medium chain signature 1. IGWRre.GikYrrNeLFLDVLE
|
| source |
prosite : PS00990
|
|
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2)
|
chain |
A |
| residue |
263-277 |
| type |
prosite |
| sequence |
ISFIPPDGEFELMRY
|
| description |
CLAT_ADAPTOR_M_2 Clathrin adaptor complexes medium chain signature 2. IsFIPPdGeFeLmrY
|
| source |
prosite : PS00991
|
|
|
3)
|
chain |
A |
| residue |
341 |
| type |
BINDING |
| sequence |
K
|
| description |
BINDING => ECO:0000305|PubMed:12086608, ECO:0000305|PubMed:25061211, ECO:0007744|PDB:2VGL, ECO:0007744|PDB:4UQI
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
A |
| residue |
345 |
| type |
BINDING |
| sequence |
K
|
| description |
BINDING => ECO:0000305|PubMed:12086608, ECO:0000305|PubMed:25061211, ECO:0007744|PDB:2VGL, ECO:0007744|PDB:4UQI
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
A |
| residue |
354 |
| type |
BINDING |
| sequence |
K
|
| description |
BINDING => ECO:0000305|PubMed:12086608, ECO:0000305|PubMed:25061211, ECO:0007744|PDB:2VGL, ECO:0007744|PDB:4UQI
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|