eF-site ID 1hmv-G PDB Code 1hmv Chain G click to enlarge Title THE STRUCTURE OF UNLIGANDED REVERSE TRANSCRIPTASE FROM THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 Classification NUCLEOTIDYLTRANSFERASE Compound HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66) Source Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1) (POL_HV1B1) Sequence G:  PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTE MEKEGKISKIGPENPYNTPVFAIVDFRELNKRTQDFWEVQ LGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFT IPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDI VIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPD KKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQ KLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEE AELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWT YQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTE SIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVN TPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYV TNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTD SQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPA HKGIGGNEQVDKLVSA Description Functional site 1) chain G residue 443 type sequence D description BINDING SITE FOR RESIDUE MG H 501 source : AC4 2) chain G residue 478 type sequence E description BINDING SITE FOR RESIDUE MG H 501 source : AC4 3) chain G residue 498 type sequence D description BINDING SITE FOR RESIDUE MG H 501 source : AC4 4) chain G residue 220 type MOD_RES sequence K description Asymmetric dimethylarginine; in Nucleocapsid protein p7; by host PRMT6 => ECO:0000269|PubMed:17415034 source Swiss-Prot : SWS_FT_FI10 5) chain G residue 242 type MOD_RES sequence Q description Asymmetric dimethylarginine; in Nucleocapsid protein p7; by host PRMT6 => ECO:0000269|PubMed:17415034 source Swiss-Prot : SWS_FT_FI10 6) chain G residue 273 type SITE sequence G description Cleavage; by viral protease => ECO:0000269|PubMed:2476069 source Swiss-Prot : SWS_FT_FI8 7) chain G residue 333 type SITE sequence G description Cleavage; by viral protease => ECO:0000269|PubMed:2476069 source Swiss-Prot : SWS_FT_FI8 8) chain G residue 196 type SITE sequence G description Cleavage; by viral protease => ECO:0000255 source Swiss-Prot : SWS_FT_FI6 9) chain G residue 210 type SITE sequence L description Cleavage; by viral protease => ECO:0000255 source Swiss-Prot : SWS_FT_FI6

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