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eF-site ID
|
1hmv-C |
|
PDB Code
|
1hmv |
|
Chain
|
C |
|
click to enlarge
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Title
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THE STRUCTURE OF UNLIGANDED REVERSE TRANSCRIPTASE FROM THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 |
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Classification
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NUCLEOTIDYLTRANSFERASE |
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Compound
|
HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66) |
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Source
|
null (POL_HV1B1) |
|
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Sequence
|
C: |
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTE
MEKEGKISKIGPENPYNTPVFAIVDFRELNKRTQDFWEVQ
LGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFT
IPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDI
VIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPD
KKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQ
KLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEE
AELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWT
YQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTE
SIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVN
TPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYV
TNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTD
SQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPA
HKGIGGNEQVDKLVSA
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Description
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Functional site
|
|
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1)
|
chain |
C |
| residue |
443 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE MG D 501
|
| source |
: AC2
|
|
|
2)
|
chain |
C |
| residue |
478 |
| type |
|
| sequence |
E
|
| description |
BINDING SITE FOR RESIDUE MG D 501
|
| source |
: AC2
|
|
|
3)
|
chain |
C |
| residue |
498 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE MG D 501
|
| source |
: AC2
|
|
|
4)
|
chain |
C |
| residue |
220 |
| type |
MOD_RES |
| sequence |
K
|
| description |
Asymmetric dimethylarginine; in Nucleocapsid protein p7; by host PRMT6 => ECO:0000269|PubMed:17415034
|
| source |
Swiss-Prot : SWS_FT_FI10
|
|
|
5)
|
chain |
C |
| residue |
242 |
| type |
MOD_RES |
| sequence |
Q
|
| description |
Asymmetric dimethylarginine; in Nucleocapsid protein p7; by host PRMT6 => ECO:0000269|PubMed:17415034
|
| source |
Swiss-Prot : SWS_FT_FI10
|
|
|
|