eF-site ID 1hjf-A PDB Code 1hjf Chain A click to enlarge Title Alteration of the co-substrate selectivity of deacetoxycephalosporin C synthase: The role of arginine-258 Classification OXIDOREDUCTASE Compound DEACETOXYCEPHALOSPORIN C SYNTHASE Source (CEFE_STRCL) Sequence A:  MDTTVPTFSLAELQQGLHQDEFRRCLRDKGLFYLTDCGLT DTELKSAKDIVIDFFEHGSEAEKRAVTSPVPTMRRGFTGL ESTGSYSDYSMCYSMGTADNLFPSGDFERIWTQYFDRQYT ASRAVAREVLRATGTEPDGGVEAFLDCEPLLRFRYFPLRM APHYDLSMVTLIQQTPFVSLQAEVGGAFTDLPYRPDAVLV FCGAIATLVTGGQVKAPRHHVAAPSQTSSVFFLRPNADFT FSVPLARECGFDVSLDGETATFQDWIGGNYVNIRRTSK Description Functional site 1) chain A residue 183 type sequence H description BINDING SITE FOR RESIDUE FE2 A 1310 source : AC1 2) chain A residue 185 type sequence D description BINDING SITE FOR RESIDUE FE2 A 1310 source : AC1 3) chain A residue 243 type sequence H description BINDING SITE FOR RESIDUE FE2 A 1310 source : AC1 4) chain A residue 162 type sequence R description BINDING SITE FOR RESIDUE COI A 1311 source : AC2 5) chain A residue 180 type sequence M description BINDING SITE FOR RESIDUE COI A 1311 source : AC2 6) chain A residue 183 type sequence H description BINDING SITE FOR RESIDUE COI A 1311 source : AC2 7) chain A residue 185 type sequence D description BINDING SITE FOR RESIDUE COI A 1311 source : AC2 8) chain A residue 192 type sequence I description BINDING SITE FOR RESIDUE COI A 1311 source : AC2 9) chain A residue 204 type sequence L description BINDING SITE FOR RESIDUE COI A 1311 source : AC2 10) chain A residue 243 type sequence H description BINDING SITE FOR RESIDUE COI A 1311 source : AC2 11) chain A residue 245 type sequence V description BINDING SITE FOR RESIDUE COI A 1311 source : AC2 12) chain A residue 262 type sequence V description BINDING SITE FOR RESIDUE COI A 1311 source : AC2 13) chain A residue 264 type sequence F description BINDING SITE FOR RESIDUE COI A 1311 source : AC2 14) chain A residue 305 type sequence I description BINDING SITE FOR RESIDUE COI A 1311 source : AC2 15) chain A residue 223-236 type prosite sequence LVFCGAIATLVTGG description IPNS_2 Isopenicillin N synthase signature 2. LVfCGAiaTlvTgG source prosite : PS00186 16) chain A residue 74 type catalytic sequence R description 137 source MCSA : MCSA1

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