eF-site ID 1hj7_20-A
PDB Code 1hj7
Model 20
Chain A

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Title NMR study of a pair of LDL receptor Ca2+ binding epidermal growth factor-like domains, 20 structures
Classification CELL-SURFACE RECEPTOR
Compound LDL RECEPTOR
Source Homo sapiens (Human) (LDLR_HUMAN)
Sequence A:  GTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCE
DIDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACK
Description (1)  LDL RECEPTOR


Functional site

1) chain A
residue 294
type
sequence T
description BINDING SITE FOR RESIDUE CA A 391
source : AC1

2) chain A
residue 296
type
sequence E
description BINDING SITE FOR RESIDUE CA A 391
source : AC1

3) chain A
residue 310
type
sequence D
description BINDING SITE FOR RESIDUE CA A 391
source : AC1

4) chain A
residue 311
type
sequence L
description BINDING SITE FOR RESIDUE CA A 391
source : AC1

5) chain A
residue 333
type
sequence D
description BINDING SITE FOR RESIDUE CA A 392
source : AC2

6) chain A
residue 334
type
sequence I
description BINDING SITE FOR RESIDUE CA A 392
source : AC2

7) chain A
residue 336
type
sequence E
description BINDING SITE FOR RESIDUE CA A 392
source : AC2

8) chain A
residue 349
type
sequence N
description BINDING SITE FOR RESIDUE CA A 392
source : AC2

9) chain A
residue 350
type
sequence L
description BINDING SITE FOR RESIDUE CA A 392
source : AC2

10) chain A
residue 308-319
type prosite
sequence CNDLKIGYECLC
description ASX_HYDROXYL Aspartic acid and asparagine hydroxylation site. CnDlkigYeClC
source prosite : PS00010

11) chain A
residue 347-358
type prosite
sequence CVNLEGGYKCQC
description ASX_HYDROXYL Aspartic acid and asparagine hydroxylation site. CnDlkigYeClC
source prosite : PS00010

12) chain A
residue 317-331
type prosite
sequence CLCPDGFQLVAQRRC
description EGF_2 EGF-like domain signature 2. ClCpdGFqlvaqrr.C
source prosite : PS01186

13) chain A
residue 356-371
type prosite
sequence CQCEEGFQLDPHTKAC
description EGF_2 EGF-like domain signature 2. ClCpdGFqlvaqrr.C
source prosite : PS01186

14) chain A
residue 333-356
type prosite
sequence DIDECQDPDTCSQLCVNLEGGYKC
description EGF_CA Calcium-binding EGF-like domain signature. DiDECqdpdt.........Csql....CvNleggYkC
source prosite : PS01187


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