|
eF-site ID
|
1hit_4-AB |
PDB Code
|
1hit |
Model
|
4 |
Chain
|
A, B |
|
click to enlarge
|
|
Title
|
Receptor binding redefined by a structural switch in a mutant Human Insulin |
Classification
|
HORMONE |
Compound
|
INSULIN |
Source
|
(INS_HUMAN) |
|
Sequence
|
A: |
GIVEQCCTSICSLYQLENYCN
|
B: |
FVNQHLCGSHLVEALYLVCGERGGFYTPKT
|
|
Description
|
(1) |
INSULIN (HUMAN) MUTANT WITH PHE B 24 REPLACED BY GLY (F24G) (NMR, REPRESENTATIVE PLUS 8 STRUCTURES)
|
|
Functional site
|
|
1)
|
chain |
A |
residue |
6-20 |
type |
prosite |
sequence |
CCTSICSLYQLENYC
|
description |
INSULIN Insulin family signature. CCTSiCSlyqLenyC
|
source |
prosite : PS00262
|
|
|
|