|
|
eF-site ID
|
1hit_1-AB |
|
PDB Code
|
1hit |
|
Model
|
1 |
|
Chain
|
A, B |
|
click to enlarge
|
|
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Title
|
Receptor binding redefined by a structural switch in a mutant Human Insulin |
|
Classification
|
HORMONE |
|
Compound
|
INSULIN |
|
Source
|
(INS_HUMAN) |
|
|
Sequence
|
A: |
GIVEQCCTSICSLYQLENYCN
|
| B: |
FVNQHLCGSHLVEALYLVCGERGGFYTPKT
|
|
|
Description
|
(1) |
INSULIN (HUMAN) MUTANT WITH PHE B 24 REPLACED BY GLY (F24G) (NMR, REPRESENTATIVE PLUS 8 STRUCTURES)
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
6-20 |
| type |
prosite |
| sequence |
CCTSICSLYQLENYC
|
| description |
INSULIN Insulin family signature. CCTSiCSlyqLenyC
|
| source |
prosite : PS00262
|
|
|
|