eF-site ID 1hdb-C PDB Code 1hdb Chain C click to enlarge Title ANALYSIS OF THE CRYSTAL STRUCTURE, MOLECULAR MODELING AND INFRARED SPECTROSCOPY OF THE DISTAL BETA-HEME POCKET VALINE67(E11)-THREONINE MUTATION OF HEMOGLOBIN Classification OXYGEN TRANSPORT Compound HEMOGLOBIN (DEOXY) BETA-V67T Source Homo sapiens (Human) (HBB_HUMAN) Sequence C:  VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTK TYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNAL SALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPA VHASLDKFLASVSTVLTSKYR Description Functional site 1) chain C residue 42 type sequence Y description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 2) chain C residue 43 type sequence F description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 3) chain C residue 45 type sequence H description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 4) chain C residue 58 type sequence H description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 5) chain C residue 83 type sequence L description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 6) chain C residue 86 type sequence L description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 7) chain C residue 87 type sequence H description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 8) chain C residue 91 type sequence L description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 9) chain C residue 93 type sequence V description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 10) chain C residue 97 type sequence N description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 11) chain C residue 98 type sequence F description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 12) chain C residue 101 type sequence L description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 13) chain C residue 136 type sequence L description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 14) chain C residue 100 type SITE sequence L description Not glycated => ECO:0000269|PubMed:7358733 source Swiss-Prot : SWS_FT_FI11 15) chain C residue 57 type SITE sequence G description Not glycated => ECO:0000269|PubMed:7358733 source Swiss-Prot : SWS_FT_FI11 16) chain C residue 61 type SITE sequence K description Not glycated => ECO:0000269|PubMed:7358733 source Swiss-Prot : SWS_FT_FI11 17) chain C residue 91 type SITE sequence L description Not glycated => ECO:0000269|PubMed:7358733 source Swiss-Prot : SWS_FT_FI11 18) chain C residue 8 type CARBOHYD sequence T description N-linked (Glc) (glycation) valine; in Hb A1c => ECO:0000269|PubMed:635569 source Swiss-Prot : SWS_FT_FI12 19) chain C residue 17 type CARBOHYD sequence V description N-linked (Glc) (glycation) valine; in Hb A1c => ECO:0000269|PubMed:635569 source Swiss-Prot : SWS_FT_FI12 20) chain C residue 41 type CARBOHYD sequence T description N-linked (Glc) (glycation) valine; in Hb A1c => ECO:0000269|PubMed:635569 source Swiss-Prot : SWS_FT_FI12 21) chain C residue 4 type MOD_RES sequence P description N-pyruvate 2-iminyl-valine; in Hb A1b source Swiss-Prot : SWS_FT_FI3 22) chain C residue 36 type MOD_RES sequence F description N-pyruvate 2-iminyl-valine; in Hb A1b source Swiss-Prot : SWS_FT_FI3 23) chain C residue 50 type MOD_RES sequence H description N-pyruvate 2-iminyl-valine; in Hb A1b source Swiss-Prot : SWS_FT_FI3 24) chain C residue 103 type MOD_RES sequence H description N6-acetyllysine; alternate => ECO:0000269|PubMed:4531009 source Swiss-Prot : SWS_FT_FI8 25) chain C residue 125 type MOD_RES sequence L description N6-acetyllysine; alternate => ECO:0000269|PubMed:4531009 source Swiss-Prot : SWS_FT_FI8 26) chain C residue 132 type MOD_RES sequence V description N6-acetyllysine; alternate => ECO:0000269|PubMed:4531009 source Swiss-Prot : SWS_FT_FI8 27) chain C residue 139 type MOD_RES sequence K description N6-acetyllysine; alternate => ECO:0000269|PubMed:4531009 source Swiss-Prot : SWS_FT_FI8

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