eF-site ID 1hcq-F PDB Code 1hcq Chain F click to enlarge Title THE CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR DNA-BINDING DOMAIN BOUND TO DNA: HOW RECEPTORS DISCRIMINATE BETWEEN THEIR RESPONSE ELEMENTS Classification TRANSCRIPTION/DNA Compound DNA (5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*CP*AP*GP*TP*GP*AP*CP*CP*T P*G)-3') Source null (1HCQ) Sequence F:  KETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGDYMC PATNQCTIDKNRRKSCQACRLRKCYEVGMMK Description Functional site 1) chain F residue 7 type sequence C description BINDING SITE FOR RESIDUE ZN F 598 source : AC7 2) chain F residue 10 type sequence C description BINDING SITE FOR RESIDUE ZN F 598 source : AC7 3) chain F residue 24 type sequence C description BINDING SITE FOR RESIDUE ZN F 598 source : AC7 4) chain F residue 27 type sequence C description BINDING SITE FOR RESIDUE ZN F 598 source : AC7 5) chain F residue 43 type sequence C description BINDING SITE FOR RESIDUE ZN F 599 source : AC8 6) chain F residue 44 type sequence P description BINDING SITE FOR RESIDUE ZN F 599 source : AC8 7) chain F residue 49 type sequence C description BINDING SITE FOR RESIDUE ZN F 599 source : AC8 8) chain F residue 59 type sequence C description BINDING SITE FOR RESIDUE ZN F 599 source : AC8 9) chain F residue 62 type sequence C description BINDING SITE FOR RESIDUE ZN F 599 source : AC8 10) chain F residue 7-72 type DNA_BIND sequence CAVCNDYASGYHYGVWSCEGCKAFFKRSIQGDYMCPATNQ CTIDKNRRKSCQACRLRKCYEVGM description Nuclear receptor => ECO:0000255|PROSITE-ProRule:PRU00407 source Swiss-Prot : SWS_FT_FI1 11) chain F residue 7-27 type ZN_FING sequence CAVCNDYASGYHYGVWSCEGC description NR C4-type => ECO:0000255|PROSITE-ProRule:PRU00407 source Swiss-Prot : SWS_FT_FI2 12) chain F residue 43-67 type ZN_FING sequence CPATNQCTIDKNRRKSCQACRLRKC description NR C4-type => ECO:0000255|PROSITE-ProRule:PRU00407 source Swiss-Prot : SWS_FT_FI2

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