eF-site ID 1hcq-A PDB Code 1hcq Chain A click to enlarge Title THE CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR DNA-BINDING DOMAIN BOUND TO DNA: HOW RECEPTORS DISCRIMINATE BETWEEN THEIR RESPONSE ELEMENTS Classification TRANSCRIPTION/DNA Compound DNA (5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*CP*AP*GP*TP*GP*AP*CP*CP*T P*G)-3') Source null (1HCQ) Sequence A:  MKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHND YMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMK Description Functional site 1) chain A residue 7 type sequence C description BINDING SITE FOR RESIDUE ZN A 598 source : AC1 2) chain A residue 10 type sequence C description BINDING SITE FOR RESIDUE ZN A 598 source : AC1 3) chain A residue 24 type sequence C description BINDING SITE FOR RESIDUE ZN A 598 source : AC1 4) chain A residue 27 type sequence C description BINDING SITE FOR RESIDUE ZN A 598 source : AC1 5) chain A residue 43 type sequence C description BINDING SITE FOR RESIDUE ZN A 599 source : AC2 6) chain A residue 49 type sequence C description BINDING SITE FOR RESIDUE ZN A 599 source : AC2 7) chain A residue 59 type sequence C description BINDING SITE FOR RESIDUE ZN A 599 source : AC2 8) chain A residue 62 type sequence C description BINDING SITE FOR RESIDUE ZN A 599 source : AC2 9) chain A residue 7-72 type DNA_BIND sequence CAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPAT NQCTIDKNRRKSCQACRLRKCYEVGM description Nuclear receptor => ECO:0000255|PROSITE-ProRule:PRU00407 source Swiss-Prot : SWS_FT_FI1 10) chain A residue 7-27 type ZN_FING sequence CAVCNDYASGYHYGVWSCEGC description NR C4-type => ECO:0000255|PROSITE-ProRule:PRU00407 source Swiss-Prot : SWS_FT_FI2 11) chain A residue 43-67 type ZN_FING sequence CPATNQCTIDKNRRKSCQACRLRKC description NR C4-type => ECO:0000255|PROSITE-ProRule:PRU00407 source Swiss-Prot : SWS_FT_FI2 12) chain A residue 7-33 type prosite sequence CAVCNDYASGYHYGVWSCEGCKAFFKR description NUCLEAR_REC_DBD_1 Nuclear hormones receptors DNA-binding region signature. CavCn.Dyasgy.HYgvwsCegCkaFFkR source prosite : PS00031

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