eF-site ID 1han-A PDB Code 1han Chain A click to enlarge Title CRYSTAL STRUCTURE OF THE BIPHENYL-CLEAVING EXTRADIOL DIOXYGENASE FROM A PCB-DEGRADING PSEUDOMONAD Classification OXIDOREDUCTASE (OXYGENASE) Compound 2,3-DIHYDROXYBIPHENYL 1,2-DIOXYGENASE Source Burkholderia xenovorans (strain LB400) (BPHC_BURCE) Sequence A:  SIRSLGYMGFAVSDVAAWRSFLTQKLGLMEAGTTDNGDLF RIDSRAWRIAVQQGEVDDLAFAGYEVADAAGLAQMADKLK QAGIAVTTGDASLARRRGVTGLITFADPFGLPLEIYYGAS EVFEKPFLPGAAVSGFLTGEQGLGHFVRCVPDSDKALAFY TDVLGFQLSDVIDMKMGPDVTVPAYFLHCNERHHTLAIAA FPLPKRIHHFMLEVASLDDVGFAFDRVDADGLITSTLGRH TNDHMVSFYASTPSGVEVEYGWSARTVDRSWVVVRHDSPS MWGHKSVR Description Functional site 1) chain A residue 146 type sequence H description ACTIVE SITE: FE(II) BINDING SITE CONSISTING IN THE FIRST SHELL OF THREE PROTEIN RESIDUES AND TWO SOLVENT SPECIES, WHICH MAY BE HOH OR OH- BUT WERE REFINED AS HOH source : FE1 2) chain A residue 210 type sequence H description ACTIVE SITE: FE(II) BINDING SITE CONSISTING IN THE FIRST SHELL OF THREE PROTEIN RESIDUES AND TWO SOLVENT SPECIES, WHICH MAY BE HOH OR OH- BUT WERE REFINED AS HOH source : FE1 3) chain A residue 260 type sequence E description ACTIVE SITE: FE(II) BINDING SITE CONSISTING IN THE FIRST SHELL OF THREE PROTEIN RESIDUES AND TWO SOLVENT SPECIES, WHICH MAY BE HOH OR OH- BUT WERE REFINED AS HOH source : FE1 4) chain A residue 146 type sequence H description BINDING SITE FOR RESIDUE FE A 500 source : AC1 5) chain A residue 210 type sequence H description BINDING SITE FOR RESIDUE FE A 500 source : AC1 6) chain A residue 260 type sequence E description BINDING SITE FOR RESIDUE FE A 500 source : AC1 7) chain A residue 189 type sequence H description BINDING SITE FOR RESIDUE FE A 501 source : AC2 8) chain A residue 202 type sequence F description BINDING SITE FOR RESIDUE TBU A 600 source : AC3 9) chain A residue 209 type sequence H description BINDING SITE FOR RESIDUE TBU A 600 source : AC3 10) chain A residue 250 type sequence Y description BINDING SITE FOR RESIDUE TBU A 600 source : AC3 11) chain A residue 280 type sequence P description BINDING SITE FOR RESIDUE TBU A 600 source : AC3 12) chain A residue 239-260 type prosite sequence GRHTNDHMVSFYASTPSGVEVE description EXTRADIOL_DIOXYGENAS Extradiol ring-cleavage dioxygenases signature. GrHtndhmvsFYasTPsGvevE source prosite : PS00082 13) chain A residue 147 type BINDING sequence F description source Swiss-Prot : SWS_FT_FI1 14) chain A residue 211 type BINDING sequence F description source Swiss-Prot : SWS_FT_FI1 15) chain A residue 261 type BINDING sequence Y description source Swiss-Prot : SWS_FT_FI1

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