eF-site ID 1h7h-AB PDB Code 1h7h Chain A, B click to enlarge Title The structure of CMP:2-keto-3-deoxy-manno-octonic acid synthetase and of its complexes with substrates and substrate analogues, CDP complex Classification NUCLEOTIDYLTRANSFERASE Compound 3-DEOXY-MANNO-OCTULOSONATE CYTIDYLYLTRANSFERASE Source (KSU5_ECOLI) Sequence A:  SKAVIVIPARYGSSRLPGKPLLDIVGKPMIQHVYERALQV AGVAEVWVATDDPRVEQAVQAFGGKAIMTRNDHESGTDRL VEVMHKVEADIYINLQGDEPMIRPRDVETLLQGMRDDPAL PVATLCHAISAAEAAEPSTVKVVVNTRQDALYFSRSPIPY PRNAEKARYLKHVGIYAYRRDVLQNYSQLPESMPEQAESL EQLRLMNAGINIRTFEVAATGPGVDTPACLEKVRALMAQE LAENA B:  SKAVIVIPARYGSSRLPGKPLLDIVGKPMIQHVYERALQV AGVAEVWVATDDPRVEQAVQAFGGKAIMTRNDHESGTDRL VEVMHKVEADIYINLQGDEPMIRPRDVETLLQGMRDDPAL PVATLCHAISAAEAAEPSTVKVVVNTRQDALYFSRSPIPY PRNAEKARYLKHVGIYAYRRDVLQNYSQLPESMPEQAESL EQLRLMNAGINIRTFEVAATGPGVDTPACLEKVRALMAQE L Description (1)  3-DEOXY-MANNO-OCTULOSONATE CYTIDYLYLTRANSFERASE (E.C.2.7.7.38) Functional site 1) chain A residue 8 type sequence P description BINDING SITE FOR RESIDUE CDP A1246 source : AC1 2) chain A residue 10 type sequence R description BINDING SITE FOR RESIDUE CDP A1246 source : AC1 3) chain A residue 19 type sequence K description BINDING SITE FOR RESIDUE CDP A1246 source : AC1 4) chain A residue 73 type sequence H description BINDING SITE FOR RESIDUE CDP A1246 source : AC1 5) chain A residue 74 type sequence E description BINDING SITE FOR RESIDUE CDP A1246 source : AC1 6) chain A residue 75 type sequence S description BINDING SITE FOR RESIDUE CDP A1246 source : AC1 7) chain A residue 79 type sequence R description BINDING SITE FOR RESIDUE CDP A1246 source : AC1 8) chain A residue 96 type sequence Q description BINDING SITE FOR RESIDUE CDP A1246 source : AC1 9) chain A residue 97 type sequence G description BINDING SITE FOR RESIDUE CDP A1246 source : AC1 10) chain A residue 98 type sequence D description BINDING SITE FOR RESIDUE CDP A1246 source : AC1 11) chain B residue 8 type sequence P description BINDING SITE FOR RESIDUE CDP B1242 source : AC2 12) chain B residue 9 type sequence A description BINDING SITE FOR RESIDUE CDP B1242 source : AC2 13) chain B residue 10 type sequence R description BINDING SITE FOR RESIDUE CDP B1242 source : AC2 14) chain B residue 19 type sequence K description BINDING SITE FOR RESIDUE CDP B1242 source : AC2 15) chain B residue 73 type sequence H description BINDING SITE FOR RESIDUE CDP B1242 source : AC2 16) chain B residue 74 type sequence E description BINDING SITE FOR RESIDUE CDP B1242 source : AC2 17) chain B residue 75 type sequence S description BINDING SITE FOR RESIDUE CDP B1242 source : AC2 18) chain B residue 79 type sequence R description BINDING SITE FOR RESIDUE CDP B1242 source : AC2 19) chain B residue 96 type sequence Q description BINDING SITE FOR RESIDUE CDP B1242 source : AC2 20) chain B residue 97 type sequence G description BINDING SITE FOR RESIDUE CDP B1242 source : AC2

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